Reply: Reference values for the Cerebellar Cognitive Affective Syndrome Scale: age and education matter.

Jeremy D Schmahmann, Mark G Vangel, Franziska Hoche, Xavier Guell, Janet C Sherman

Abstract readLetterComment

In one paragraph

Article in Brain : a journal of neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it

0cells of the map it votes in

9citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

Cerebellar clinical syndromes: the triad and rating scales.Journal of neurology · 2026
Review
The Italian Standardization of the Cerebellar Cognitive Affective/Schmahmann Syndrome Scale: Cognitive Profiling in a Healthy, Heterogeneous Population.Cerebellum (London, England) · 2025
Article
The Cerebellar Cognitive Affective/Schmahmann Syndrome Scale: Updates and Insights.Cerebellum (London, England) · 2025
Article
The cerebellar-related cognitive function is sensitive to aging: implications for early detection.Frontiers in aging neuroscience · 2025
Article
Reliability and validity study of the Chinese version of the Cerebellar Cognitive Affective Syndrome Scale in patients with cerebellar injury.Acta neurologica Belgica · 2024
Article
The Cerebellar Cognitive Affective/Schmahmann Syndrome Scale in Spinocerebellar Ataxias.Cerebellum (London, England) · 2024
Article
Dimensions of Formal Thought Disorder and Their Relation to Gray- and White Matter Brain Structure in Affective and Psychotic Disorders.Schizophrenia bulletin · 2022
Article
Cognitive Decline Is Closely Associated with Ataxia Severity in Spinocerebellar Ataxia Type 2: a Validation Study of the Schmahmann Syndrome Scale.Cerebellum (London, England) · 2022
Article
Triple representation of language, working memory, social and emotion processing in the cerebellum: convergent evidence from task and seed-based resting-state fMRI analyses in a single large cohort.NeuroImage · 2018
Article

4 · The record

Corrections and comments

Comment on
The cerebellar cognitive affective/Schmahmann syndrome scale.2018
Comment on
Reference values for the Cerebellar Cognitive Affective Syndrome Scale: age and education matter.2021

5 · Who and what money

Authors and funding

5 authors.

Jeremy D SchmahmannAtaxia Center, Cognitive Behavioral Neurology Unit, Laboratory for Neuroanatomy and Cerebellar Neurobiology, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

Mark G VangelMartinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

Franziska HocheAtaxia Center, Cognitive Behavioral Neurology Unit, Laboratory for Neuroanatomy and Cerebellar Neurobiology, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

Xavier GuellAtaxia Center, Cognitive Behavioral Neurology Unit, Laboratory for Neuroanatomy and Cerebellar Neurobiology, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

Janet C ShermanPsychology Assessment Center, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cerebellar DiseasesCognition DisordersCognitionHumansReference Values

Identifiers

PMID33313688

DOI10.1093/brain/awaa419

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.