ArticleBioactive materials2021
Bio-inspired intestinal scavenger from microfluidic electrospray for detoxifying lipopolysaccharide.
Article in Bioactive materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 50 citations in OpenAlex.
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- Micro/nano motors treating of digestive system diseases.Journal of nanobiotechnology · 2025Review
- Effect of microencapsulation techniques on the different properties of bioactives, vitamins and minerals.Food science and biotechnology · 2024Review
- Developing functional hydrogels for treatment of oral diseases.Smart medicine · 2024Review
- Encapsulation of Bioactive Peptides by Spray-Drying and Electrospraying.Foods (Basel, Switzerland) · 2023Review
- Ultrasound-trigged micro/nanorobots for biomedical applications.Smart medicine · 2023Review
- Application of Biomedical Microspheres in Wound Healing.International journal of molecular sciences · 2023Review
- Bioinspired Jellyfish Microparticles from Microfluidics.Research (Washington, D.C.) · 2023Article
- Abalone-Inspired Adhesive and Photo-Responsive Microparticle Delivery Systems for Periodontal Drug Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Design and aligner-assisted fast fabrication of a microfluidic platform for quasi-3D cell studies on an elastic polymer.Bioactive materials · 2022Article
- Research Progress on Emerging Polysaccharide Materials Applied in Tissue Engineering.Polymers · 2022Review
- Biopolymer-Based Multilayer Microparticles for Probiotic Delivery to Colon.Advanced healthcare materials · 2022Review
- Current Understanding of the Applications of Photocrosslinked Hydrogels in Biomedical Engineering.Gels (Basel, Switzerland) · 2022Review
- Promising Applications of Nanoparticles in the Treatment of Hearing Loss.Frontiers in cell and developmental biology · 2021Review
- Responsive Janus Structural Color Hydrogel Micromotors for Label-Free Multiplex Assays.Research (Washington, D.C.) · 2021Article
- Long-Term Release of Dexamethasone With a Polycaprolactone-Coated Electrode Alleviates Fibrosis in Cochlear Implantation.Frontiers in cell and developmental biology · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lipopolysaccharide (LPS) plays an important role in metabolic syndrome (MetS) and other gut-derived diseases, and detoxifying LPS is considered to be a fundamental approach to prevent and treat these diseases. Here, inspired by the feeding behaviour of scavenger, novel microfluidic microcapsules with alkaline phosphatase (ALP) encapsulation and the scavenger-like molecular sieve shell are presented for cleaning intestinal LPS. Benefiting from the precisely controlled of the pore size and microfluidic electrospray, the generated microcapsules were imparted with porous molecular-sieve shells and ALP encapsulated active cores. These microcapsules could continuously work as an intestinal scavenger after colonized in intestine. It has been demonstrated that the microcapsules could englobe LPS while inhibit the permeation of digestive enzyme, and this ability contributes to promising ALP's activity, protecting cells at the presence of LPS and reducing inflammation. In addition, this scavenger inspired microcapsule could effectively decrease the LPS in organs, reduce inflammation and regulating fat metabolism
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.