Evidence map›Paper›PMID 33313377›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2020

Evaluation of a visual interpretation method for tau-PET with

Ida Sonni, Orit H Lesman Segev, Suzanne L Baker, Leonardo Iaccarino, Deniz Korman, Gil D Rabinovici, William J Jagust, Susan M Landau, Renaud La Joie, Alzheimer's Disease Neuroimaging Initiative

Abstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Investigating AD and non-AD [European journal of nuclear medicine and molecular imaging · 2026
    Article
  4. Visual versus quantitative tau-PET Braak staging in Alzheimer's disease using [European journal of nuclear medicine and molecular imaging · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Exploring microtubule dynamics in Alzheimer's disease: Longitudinal assessment using [Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Performance of a [Neurology · 2023
    Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ida SonniMolecular Biophysics and Integrated Bioimaging Lawrence Berkeley National Lab Berkeley California USA.ORCID https://orcid.org/0000-0002-8802-7704
Orit H Lesman SegevMemory and Aging Center University of California, San Francisco San Francisco California USA.
Suzanne L BakerMolecular Biophysics and Integrated Bioimaging Lawrence Berkeley National Lab Berkeley California USA.
Leonardo IaccarinoMemory and Aging Center University of California, San Francisco San Francisco California USA.
Deniz KormanHelen Wills Neuroscience Institute University of California, Berkeley Berkeley California USA.
Gil D RabinoviciMolecular Biophysics and Integrated Bioimaging Lawrence Berkeley National Lab Berkeley California USA.
William J JagustMolecular Biophysics and Integrated Bioimaging Lawrence Berkeley National Lab Berkeley California USA.
Susan M LandauHelen Wills Neuroscience Institute University of California, Berkeley Berkeley California USA.
Renaud La JoieMemory and Aging Center University of California, San Francisco San Francisco California USA.ORCID https://orcid.org/0000-0003-2581-8100
Alzheimer's Disease Neuroimaging Initiative

Funding

Research Education ComponentP30AG062422 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HOWARD J ROSEN · 2019 to 2026
$36.9M
Neural and Biochemical Mechanisms of Cognitive AgingR01AG034570 · NIA · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI William J. Jagust · 2009 to 2026
$12.0M
Connectome-based spread of neurodegenerative processes in Alzheimer's diseaseK99AG065501 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LA JOIE, RENAUD CHARLES · 2020 to 2021
$253k
NIA NIH HHS K99 AG065501NIA NIH HHS P30 AG062422NIA NIH HHS R01 AG034570
6 · The paper itself

Abstract

introductionPositron emission tomography targeting tau (tau-PET) is a promising diagnostic tool for the identification of Alzheimer's disease (AD). Currently available data rely on quantitative measures, and a visual interpretation method, critical for clinical translation, is needed.

methodsWe developed a visual interpretation method for

resultsGlobal visual scores were reliable, correlated with global cortical DISCUSSION: This

Indexed as

Alzheimer's diseaseflortaucipirqualitative assessmenttau positron emission tomographyvisual assessment

Identifiers

PMID33313377
PMCPMC7699207

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.