Evidence map›Paper›PMID 33313320›Full record

ArticleBioMed research international2020

Combined High Resistin and EGFR Expression Predicts a Poor Prognosis in Breast Cancer.

Yue Zeng, Chih-Hsin Tang, Yan Wang, Hua-Jun Lu, Bi-Fei Huang, Qian Wang, Jun-Kang Shao, Lu-Lu Jin, Chao-Qun Wang, Li-Song Teng

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Yue Zeng *Department of Surgical Oncology, The First Affiliated Hospital, Medical School of Zhejiang University, Hangzhou, Zhejiang, China.
Chih-Hsin Tang *Graduate Institute of Basic Medical Science, China Medical University, Taichung, Taiwan.
Yan WangDepartment of Medical Oncology, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, Zhejiang, China.
Hua-Jun LuDepartment of Oncological Radiotherapy, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, Zhejiang, China.
Bi-Fei HuangDepartment of Pathology, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, Zhejiang, China.
Qian WangDepartment of Pathology, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, Zhejiang, China.
Jun-Kang ShaoDepartment of Pathology, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, Zhejiang, China.
Lu-Lu JinLaboratory of Biomedicine, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, Zhejiang, China.
Chao-Qun WangDepartment of Pathology, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, Zhejiang, China.ORCID https://orcid.org/0000-0001-9912-9477
Li-Song TengDepartment of Surgical Oncology, The First Affiliated Hospital, Medical School of Zhejiang University, Hangzhou, Zhejiang, China.ORCID https://orcid.org/0000-0003-3151-2001
Wenzhou Medical University · CNAsia University · TWZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elevated levels of resistin and epidermal growth factor receptor (EGFR) facilitate the development of breast cancer, although there are no reports of any correlation between these proteins. This study analyzed 392 human breast cancer tissue specimens and 42 samples of adjacent normal tissue. Rates of positive and strongly positive resistin expression were significantly higher in breast cancer tissue than in the adjacent nontumor tissue (83.2% vs. 23.8% and 20.9% vs. 0.0%, respectively;

Indexed as

AdultAgedAged, 80 and overBiomarkers, TumorBreast NeoplasmsDisease-Free SurvivalErb-b2 Receptor Tyrosine KinasesErbB ReceptorsEstrogen Receptor alphaFemaleGene Expression ProfilingGene Expression Regulation, NeoplasticHumansImmunohistochemistryMiddle AgedNeoplasm Recurrence, LocalBiomarkers, TumorEGFR protein, humanERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesErbB ReceptorsESR1 protein, humanEstrogen Receptor alphaReceptors, ProgesteroneResistinRETN protein, human

Identifiers

PMID33313320
PMCPMC7719526
OpenAlexW3107017745

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.