Evidence map›Paper›PMID 33313314›Full record

ReviewBioMed research international2020

Growing Evidence of Exosomal MicroRNA-Related Metastasis of Hepatocellular Carcinoma.

Wenbing Sun, Shuqi Fu, Size Wu, Rong Tu

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Wenbing SunDepartment of Medical Imaging, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan 570102, China.ORCID https://orcid.org/0000-0002-1697-9204
Shuqi FuDepartment of Medical Imaging, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan 570102, China.ORCID https://orcid.org/0000-0001-9260-3279
Size WuDepartment of Medical Imaging, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan 570102, China.ORCID https://orcid.org/0000-0002-1086-764X
Rong TuDepartment of Medical Imaging, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan 570102, China.ORCID https://orcid.org/0000-0002-0030-4376
Hainan Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metastasis is the prominent cause of death in patients with hepatocellular carcinoma (HCC); however, the mechanisms behind HCC metastasis are not well understood. MicroRNAs (miRs) can regulate gene expression and affect HCC metastasis. Exosomes can transport miRs and other cargoes to and from different cells, thus being associated with tumour-distant metastasis. Exosomal miRs involve different processes of HCC metastasis through their functional effects, such as their induction of epithelial-to-mesenchymal transition, angiogenesis, and distant niche. In this review, data from the literature were analysed and summarised, with a focus on the evidence extraction of exosomal miRs in HCC metastasis with the purpose of increasing the understanding of the mechanisms behind HCC metastasis and acquiring implications for application.

Indexed as

AnimalsCarcinoma, HepatocellularCell Line, TumorCell ProliferationDisease ProgressionEpithelial-Mesenchymal TransitionExosomesGene Expression Regulation, NeoplasticHumansLiver NeoplasmsMiceMicroRNAsNeoplasm MetastasisNeoplasm TransplantationNeovascularization, PathologicSignal TransductionMicroRNAs

Identifiers

PMID33313314
PMCPMC7719499
OpenAlexW3107523577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.