Evidence map›Paper›PMID 33313310›Full record

ArticleBioMed research international2020

Cord Blood Levels of Angiopoietin-Like 7 (ANGPTL7) in Preterm Infants.

Xin Xia, Zhuxiao Ren, Longli Yan, Xuaner Zheng, Haoming Yang, Memnmeng Kang, Huiheng Yan, Zhicheng Zhong, Fang Xu, Jiayu Miao and 4 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Xin XiaDepartment of Neonatology, Guangdong Women and Children Hospital, Guangzhou Medical University, Guangzhou, China.
Zhuxiao RenDepartment of Neonatology, Guangdong Women and Children Hospital, Guangzhou Medical University, Guangzhou, China.
Longli YanDepartment of Neonatology, Guangdong Women and Children Hospital, Guangzhou Medical University, Guangzhou, China.
Xuaner ZhengDepartment of Neonatology, Guangdong Women and Children Hospital, Guangzhou Medical University, Guangzhou, China.
Haoming YangDepartment of Neonatology, Guangdong Women and Children Hospital, Guangzhou Medical University, Guangzhou, China.
Memnmeng KangDepartment of Neonatology, Guangdong Women and Children Hospital, Guangzhou Medical University, Guangzhou, China.
Huiheng YanDepartment of Neonatology, Guangdong Women and Children Hospital, Guangzhou Medical University, Guangzhou, China.
Zhicheng ZhongDepartment of Clinical Genetic Center, Guangdong Women and Children Hospital, Guangzhou Medical University, Guangzhou, China.
Fang XuDepartment of Neonatology, Guangdong Women and Children Hospital, Guangzhou Medical University, Guangzhou, China.
Jiayu MiaoDepartment of Neonatology, Guangdong Women and Children Hospital, Guangzhou Medical University, Guangzhou, China.
Jianlan WangDepartment of Neonatology, Guangdong Women and Children Hospital, Guangzhou Medical University, Guangzhou, China.
Yongsheng LiGuangdong Cord Blood and Stem Cell Bank, Guangzhou, China.
Wei WeiGuangdong Cord Blood and Stem Cell Bank, Guangzhou, China.
Jie YangDepartment of Neonatology, Guangdong Women and Children Hospital, Guangzhou Medical University, Guangzhou, China.ORCID https://orcid.org/0000-0002-7691-0241
Guangdong Province Women and Children Hospital · CNGuangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveANGPTL7 is a member of the angiogenin-like protein family. Compared to other members, ANGPTL7 is the least known. Recent studies have explored the relationship between ANGPTL7 and multiple pathological processes and diseases. However, there is no research about ANGPTL7 in neonates. This study was designed to investigate the concentration of ANGPTL7 in cord blood of preterm infants.

methodSingleton infants born in November 2017 to June 2019 in the study hospital were enrolled in the study. Maternal and neonatal clinical data were collected. ANGPTL7 levels in cord blood and serum on the third day after birth were measured by an enzyme-linked immunosorbent assay.

resultA total of 182 infants were enrolled in this study. Patients were categorized into two groups by gestational age (102 preterm, 80 full-term). ANGPTL7 levels in preterm infants were significantly higher than that in full-term babies (

conclusionCord blood ANGPTL7 levels are higher in preterm infants than full-term babies. The levels are independently influenced by gestational ages and attenuated significantly after birth. The underlying mechanism needs to be further studied.

Indexed as

Infant, PrematureAdultAngiopoietin-Like Protein 7Angiopoietin-like ProteinsEnzyme-Linked Immunosorbent AssayFemaleFetal BloodHumansInfant, NewbornMaleMaternal AgeMothersRegression AnalysisAngiopoietin-Like Protein 7Angiopoietin-like ProteinsANGPTL7 protein, human

Identifiers

PMID33313310
PMCPMC7719486
OpenAlexW3108081620

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.