Evidence map›Paper›PMID 33313184›Full record

ArticleAnnals of translational medicine2020

Iodine nutrition and prevalence of sonographic thyroid findings in adults in the Heilongjiang Province, China.

Kuo Miao, Liwei Zhang, Xiaoqiu Dong, Yunfeng Qi, Dejiao Kong, Ying Liu, Ning Zhao, Jing Hu

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 81% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kuo MiaoDepartment of Ultrasound, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
Liwei ZhangDepartment of Ultrasound, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
Xiaoqiu DongDepartment of Ultrasound, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
Yunfeng QiDepartment of Ultrasound, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
Dejiao KongDepartment of Ultrasound, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
Ying LiuKey Laboratory of Etiology and Epidemiology, National Health and Family Planning Commission, Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, China.
Ning ZhaoDepartment of Ultrasound, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
Jing HuCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China.
Harbin Medical University · CNFourth Affiliated Hospital of Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThyroid disease and thyroid nodules are common clinical problems. Iodine nutrition plays an important role in thyroid disease evolution. Here, we aimed to estimate the iodine nutritional status and prevalence of thyroid disease in the adults of the Heilongjiang Province in northeast China.

methodsWe performed a cross-sectional ultrasound (US)-based survey on volunteers aged 20-70 years from 30 regions of the Heilongjiang Province. The participants were recruited using the probability proportional to size (PPS) method, and consent for US screening was obtained from them. The survey was performed by trained technicians using the same US equipment with a 6-15 MHz linear transducer (MyLab 30 cv, Italy) and was hosted in public community locations such as local hospitals and outpatient departments. Information on basic demographic characteristics, such as urinary iodine and iodine intake were collected. The age- and sex-adjusted prevalence of thyroid disease was determined through direct standardization and reported using the province's population in 2016 as reference.

resultsFrom December 12, 2017, to March 10, 2019, 3,754 participants with a mean age of 48.65 (±12.39) years participated in the study. Of them, 3,643 had reliable urinary iodine data. The median urinary iodine and salt iodine concentrations within the normal range were 163.30 µg/L and 24.30 mg/kg, respectively. The age- and sex-adjusted prevalence of thyroid disease was 52.91%. Diffuse thyroid disease (DTD), focal thyroid lesions (FTL), and coexistence of both diseases were prevalent in 8.68%, 36.58%, and 7.65% of the participants, respectively. The prevalence of the five categories according to US-based survey features in the ACR TI-RADS (i.e., TR1, TR2, TR3, TR4, and TR5) was 7.71%, 14.53%, 3.44%, 14.82%, and 3.51%, and the prevalence of nodules that needed fine-needle aspiration was 2.55%.

conclusionsIn Heilongjiang Province, adults aged 20-70 years belong to the optimal iodine status. Further, the salt iodine levels are in the normal range. Thyroid diseases are highly prevalent in this age group; however, the intervention rate is low. We provided population-based estimates of the prevalence of thyroid disease and the iodine status in adults of Heilongjiang Province. These findings are useful to support effective intervention planning for thyroid disease.

Indexed as

iodine nutritionPrevalencesalt iodinethyroidultrasound (US)

Identifiers

PMID33313184
PMCPMC7723618
OpenAlexW3092086591

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.