Evidence map›Paper›PMID 33313112›Full record

ArticleAnnals of translational medicine2020

The role of artificial intelligence in identifying asthma in pediatric inpatient setting.

Gang Yu, Zheming Li, Shuxian Li, Jingling Liu, Moyuan Sun, Xiaoqing Liu, Fenglei Sun, Jie Zheng, Yiming Li, Yizhou Yu and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. The evolution of scientific knowledge in childhood asthma over time.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  4. Article
  5. Impact of varying childhood asthma definitions on incidence and clinical outcomes.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2026
    Article
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  7. Article
  8. Review
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  11. AI model for predicting asthma prognosis in children.The journal of allergy and clinical immunology. Global · 2025
    Article
  12. Review
  13. Review
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Gang YuDepartment of IT Center, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zheming LiDepartment of IT Center, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Shuxian LiDepartment of Pulmonology, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jingling LiuDepartment of Pulmonology, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Moyuan SunDeepWise AI Lab, Beijing, China.
Xiaoqing LiuDeepWise AI Lab, Beijing, China.
Fenglei SunDeepWise AI Lab, Beijing, China.
Jie ZhengDeepWise AI Lab, Beijing, China.
Yiming LiDeepWise AI Lab, Beijing, China.
Yizhou YuDeepWise AI Lab, Beijing, China.
Qiang ShuNational Clinical Research Center for Child Health, Hangzhou, China.
Yingshuo WangDepartment of Pulmonology, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Children's Hospital of Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of asthma in Chinese children has rapidly increased as a result of inadequate management. This is mainly due to the failure of many primary-level pediatricians to distinguish asthma from common respiratory diseases, such as bronchitis and pneumonia. Such misdiagnoses often lead to the abuse of antibiotics and systemic glucocorticoids. Additionally, if asthma is not diagnosed early, chronic airway inflammation results in lesions that not only hamper children's athletic abilities, but serve as the primary cause for adult chronic airway diseases, such as chronic obstructive pulmonary disease (COPD).

methodsA number of machine learning-based models including CatBoost, Logistic Regression, Naïve Bayes, and Support Vector Machines (SVM) have been developed to identify asthma via utilizing retrospective electronic medical records (EMRs) of patients. These models were evaluated independently using EMRs from both the Pulmonology Department and other departments of the Children's Hospital, Zhejiang University School of Medicine, China.

resultsTwo independent test sets were applied for performance evaluation. TestSet-1 consisted of 325 positive asthma cases and 428 negative cases from the Pulmonology Department. TestSet-2 was composed of 2,123 cases from non-pulmonology departments, and included 337 positive and 1,786 negative cases. Experimental results showed that the CatBoost model outperformed other models on both test sets with an accuracy of 84.7% and an area under the curve (AUC) of 90.9% on TestSet-1, and an accuracy of 96.7% and an AUC of 98.1% on TestSet-2.

conclusionsThe artificial intelligence (AI) model could rapidly and accurately identify asthma in general medical wards of children, and may aid primary pediatricians in the correct diagnoses of asthma. It possesses great clinical value and practical significance in improving the control rate of asthma in children, optimizing medical resources, and limiting the abuse of antibiotics and systemic glucocorticoids.

Indexed as

artificial intelligence (AI)asthmadiagnostic assistantmachine learningPediatric

Identifiers

PMID33313112
PMCPMC7723595
OpenAlexW3096494132

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.