Evidence map›Paper›PMID 33313088›Full record

ArticleAnnals of translational medicine2020

Egg consumption and health outcomes: a global evidence mapping based on an overview of systematic reviews.

Xianzhuo Zhang, Meng Lv, Xufei Luo, Janne Estill, Ling Wang, Mengjuan Ren, Yunlan Liu, Ziyun Feng, Jianjian Wang, Xiaohui Wang and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06405360 (DEUX OEUFs), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06405360 naterminatednot on this mapstarted 2024, after this paper: background citation

DEUX OEUFs:Cracking the Potential of Eggs to Improve Child Growth and Development

TypeinterventionalSponsorUniversity of FloridaRan2024 to 2026Enrolled464ConditionsInfant Malnutrition, Fetal Growth RetardationArmsEgg consumption
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xianzhuo ZhangThe First School of Clinical Medicine, Lanzhou University, Lanzhou, China.
Meng LvSchool of Public Health, Lanzhou University, Lanzhou, China.
Xufei LuoSchool of Public Health, Lanzhou University, Lanzhou, China.
Janne EstillInstitute of Global Health, University of Geneva, Geneva, Switzerland.
Ling WangSchool of Public Health, Lanzhou University, Lanzhou, China.
Mengjuan RenSchool of Public Health, Lanzhou University, Lanzhou, China.
Yunlan LiuSchool of Public Health, Lanzhou University, Lanzhou, China.
Ziyun FengThe First School of Clinical Medicine, Lanzhou University, Lanzhou, China.
Jianjian WangSchool of Public Health, Lanzhou University, Lanzhou, China.
Xiaohui WangSchool of Public Health, Lanzhou University, Lanzhou, China.
Yaolong ChenSchool of Public Health, Lanzhou University, Lanzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral systematic reviews and meta-analyses have assessed the association between egg consumption and human health, but the evidence is often conflicting.

methodsWe conducted a systematic literature search to find all systematic reviews and meta-analyses that assess the association between egg consumption and any type of health outcome. We used AMSTAR to evaluate the methodological quality of the reviews, and GRADE to determine the quality of evidence. We visualized the results using a human anatomy diagram and evidence mapping.

resultsOur search revealed 29 systematic reviews and meta-analyses. Eight studies were of high methodological quality, 16 studies of medium quality, and five studies of low quality. We identified 34 primary outcomes from the included 29 reviews, which were combined into a total of 22 different health outcomes. Two of the primary outcomes were based on high-quality evidence, 18 on moderate-quality evidence, and 14 on low-quality evidence. Egg consumption was associated with an increased risk of two diseases and decreased risk of six outcomes. For ten outcomes, no significant association was found, and for four outcomes, different reviews came to conflicting conclusions.

conclusionsThe association between egg consumption and the risk of cancer, diabetes, cardiovascular diseases and other related diseases has been studied in several meta-analyses. The evidence from different studies on the same topic was often conflicting, which can complicate the making of dietary recommendations.

Indexed as

Egg consumptionevidence mappinghuman healthsystematic reviewumbrella review

Identifiers

PMID33313088
PMCPMC7723562

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.