Evidence map›Paper›PMID 33312901›Full record

ArticleAnnals of cardiothoracic surgery2020

Overcoming the transcatheter aortic valve replacement Achilles heel: conduction abnormalities-a systematic review.

Alberto Alperi, Guillem Muntané-Carol, Afonso B Freitas-Ferraz, Lucia Junquera, David Del Val, Laurent Faroux, François Philippon, Josep Rodés-Cabau

Open access · diamondAbstract read
In one paragraph

Article in Annals of cardiothoracic surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Alberto AlperiQuebec Heart & Lung Institute, Laval University, Quebec City, Quebec, Canada.
Guillem Muntané-CarolQuebec Heart & Lung Institute, Laval University, Quebec City, Quebec, Canada.
Afonso B Freitas-FerrazQuebec Heart & Lung Institute, Laval University, Quebec City, Quebec, Canada.
Lucia JunqueraQuebec Heart & Lung Institute, Laval University, Quebec City, Quebec, Canada.
David Del ValQuebec Heart & Lung Institute, Laval University, Quebec City, Quebec, Canada.
Laurent FarouxQuebec Heart & Lung Institute, Laval University, Quebec City, Quebec, Canada.
François PhilipponQuebec Heart & Lung Institute, Laval University, Quebec City, Quebec, Canada.
Josep Rodés-CabauQuebec Heart & Lung Institute, Laval University, Quebec City, Quebec, Canada.
Université Laval · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTranscatheter aortic valve replacement (TAVR) has been shown to be a good alternative to surgery for treating severe symptomatic aortic stenosis (AS) across the whole range of surgical risk patients. Whereas most periprocedural TAVR complications have significantly decreased over time, conduction disturbances remain high. Approaches to decrease this shortcoming are under continuous investigation.

methodsWe conducted a systematic review focusing on modifiable factors impacting post-TAVR conduction disturbances, such as balloon aortic valvuloplasty (BAV), type of new-generation transcatheter valve and implantation depth (ID). Search strategies were based on the best available evidence from each study. Primary endpoints were post-TAVR need of permanent pacemaker implantation (PPI) and new onset left bundle branch block (NOLBBB).

resultsData from 35 studies with a total of 29,982 patients were analyzed. BAV did not negatively impact PPI rates after TAVR. In propensity-matched and randomized trials, the Evolut R valve was associated with higher rates of PPI compared to the Sapien 3 valve (25%

conclusionsPre-TAVR BAV did not increase the risk of conduction disturbances post-TAVR. Among the new-generation transcatheter valve systems, Sapien 3 and Acurate Neo valves were associated with the lowest PPI rates followed by the Evolut and Portico valves. A deeper valve implantation and a shorter MS length determined an increased risk of conduction disturbances post-TAVR.

Indexed as

conduction disturbancesleft bundle branch blockpacemakerTranscatheter aortic valve replacement (TAVR)

Identifiers

PMID33312901
PMCPMC7724069
OpenAlexW3034677290

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.