Evidence map›Paper›PMID 33312883›Full record

ReviewWorld journal of clinical oncology2020

Liquid biopsy in ovarian cancer: Catching the silent killer before it strikes.

Laura Feeney, Ian Jg Harley, W Glenn McCluggage, Paul B Mullan, James P Beirne

Open access · diamondAbstract readReview
In one paragraph

Review in World journal of clinical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
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  5. Contemporary risk assessment and risk-reducing strategies for tubo-ovarian cancer in women with BRCA pathogenic variants.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Laura FeeneyPatrick G Johnston Centre for Cancer Research, Queens University, Belfast BT9 7AE, United Kingdom.
Ian Jg HarleyNorthern Ireland Gynaecological Cancer Centre, Belfast Health and Social Care Trust, Belfast BT9 7AB, United Kingdom.
W Glenn McCluggageDepartment of Pathology, Belfast Health and Social Care Trust, Belfast BT12 6BL, United Kingdom.
Paul B MullanPatrick G Johnston Centre for Cancer Research, Queens University, Belfast BT9 7AE, United Kingdom.
James P BeirneTrinity St James Cancer Institute, St. James' Hospital, Dublin 8, Ireland. jbeirne@stjames.ie.
Belfast Health and Social Care Trust · GBQueen's University Belfast · GBSt. James's Hospital · IE

Funding

Cancer Research UK 28145Medical Research Council MC_PC_17175
6 · The paper itself

Abstract

Epithelial ovarian cancer (EOC) is the most lethal gynaecological malignancy in the western world. The majority of women presenting with the disease are asymptomatic and it has been dubbed the "silent killer". To date there is no effective minimally invasive method of stratifying those with the disease or screening for the disease in the general population. Recent molecular and pathological discoveries, along with the advancement of scientific technology, means there is a real possibility of having disease-specific liquid biopsies available within the clinical environment in the near future. In this review we discuss these discoveries, particularly in relation to the most common and aggressive form of EOC, and their role in making this possibility a reality.

Indexed as

Biomarker discoveryCirculating tumor DNAEpithelial ovarian cancerLiquid biopsyMolecular profilePrecision medicine

Identifiers

PMID33312883
PMCPMC7701910
OpenAlexW3104376072

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.