ArticleTranslational neuroscience2020
High-fat diet-induced obesity and impairment of brain neurotransmitter pool.
Article in Translational neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 55 citations in OpenAlex.
- Combined Lutein and Exercise Intervention Alleviates Brain Alteration Induced by a High-Fat Diet in Obese Rats.Food science & nutrition · 2026Article
- The association between medial prefrontal GABA concentration and memory performance is disrupted in human with a high body mass index.Brain imaging and behavior · 2026Article
- Effects of Cardamom on Neuroinflammation, Learning and Memory in Mice Fed a Cafeteria Diet.Endocrinology, diabetes & metabolism · 2026Article
- Diet-induced obesity impairs refeeding responses and downregulates lateral septal GLP-1R in male rats: an effect reversed by weight-loss treatment.Frontiers in pharmacology · 2026Article
- The Study of Approaches to Modeling Oxidative Stress in Male Wistar Rats: The Comparative Analysis of Diet-Induced, Chemically Induced, and Physiologically Induced Models.International journal of molecular sciences · 2025Article
- Neuropsychiatric Abnormalities in Metabolic Disturbances: Interplay of Adipokines and Neurotransmission.Molecular neurobiology · 2025Review
- Nutraceuticals for Gut-Brain Axis Health: A Novel Approach to Combat Malnutrition and Future Personalised Nutraceutical Interventions.Nutrients · 2025Review
- Blood metabolome shows signatures of metabolic dysregulation in obese and overweight subjects that can be predicted by machine learning applied to heart rate variability.Frontiers in molecular biosciences · 2025Article
- Crosstalk between MSC-extracellular vesicles andFrontiers in pharmacology · 2025Article
- Hippocampal Leptin Resistance and Cognitive Decline: Mechanisms, Therapeutic Strategies and Clinical Implications.Biomedicines · 2024Review
- Omega-3 Attenuates Disrupted Neurotransmission and Partially Protects Metabolic Dysfunction Caused by Obesity in Wistar Rats.Neurochemical research · 2024Article
- Body and mind: how obesity triggers neuropsychiatric and neurodegenerative disorders.Frontiers in psychiatry · 2024Article
- Discrimination exposure impacts unhealthy processing of food cues: crosstalk between the brain and gut.Nature. Mental health · 2023Article
- Effect of vitamin D3 on lipid droplet growth in adipocytes of mice with HFD-induced obesity.Food science & nutrition · 2023Article
- Review of Plant Extracts and Active Components: Mechanisms of Action for the Treatment of Obesity-Induced Cognitive Impairment.Brain sciences · 2023Review
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- Effect of berrycactus fruit (Open life sciences · 2023Article
- Potential novel biomarkers in small intestine for obesity/obesity resistance revealed by multi-omics analysis.Lipids in health and disease · 2022Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity and the brain are linked since the brain can control the weight of the body through its neurotransmitters. The aim of the present study was to investigate the effect of high-fat diet (HFD)-induced obesity on brain functioning through the measurement of brain glutamate, dopamine, and serotonin metabolic pools. In the present study, two groups of rats served as subjects. Group 1 was fed a normal diet and named as the lean group. Group 2 was fed an HFD for 4 weeks and named as the obese group. Markers of oxidative stress (malondialdehyde, glutathione, glutathione-
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.