ArticleEvolution letters2020
Experimental evidence for stabilizing selection on virulence in a bacterial pathogen.
Article in Evolution letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 28 citations in OpenAlex.
- Article
- Paying Upfront: Successful Initial Infections Protect Against Severe Future Infections.Integrative organismal biology (Oxford, England) · 2026Article
- Variability in infection dynamics emerges from the interplay between unique host and pathogen characteristics.Scientific reports · 2025Article
- Pathogen priming alters host transmission potential and predictors of transmissibility in a wild songbird species.mSphere · 2025Article
- Host Disease Tolerance Predicts Transmission Probability for a Songbird Pathogen.Ecology and evolution · 2025Article
- Increased preference for lysine over arginine in spike proteins of SARS-CoV-2 BA.2.86 variant and its daughter lineages.PloS one · 2025Article
- Evolution of the CRISPR-Cas9 defence system inMicrobial genomics · 2024Article
- Pathogen priming alters host transmission potential and predictors of transmissibility in a wild songbird species.bioRxiv : the preprint server for biology · 2024Article
- Links between Innate and Adaptive Immunity Can Favor Evolutionary Persistence of Immunopathology.Integrative and comparative biology · 2024Article
- Article
- Combined reference-free and multi-reference based GWAS uncover cryptic variation underlying rapid adaptation in a fungal plant pathogen.PLoS pathogens · 2023Article
- Let's stick together: Infection enhances preferences for social grouping in a songbird species.Ecology and evolution · 2023Article
- Rapid adaptation to a novel pathogen through disease tolerance in a wild songbird.PLoS pathogens · 2023Article
- Limited host availability disrupts the genetic correlation between virulence and transmission.Evolution letters · 2023Article
- High virulence is associated with pathogen spreadability in a songbird-bacterial system.Royal Society open science · 2023Article
- Shoaling guppies evade predation but have deadlier parasites.Nature ecology & evolution · 2022Article
- Disease tolerance alters host competence in a wild songbird.Biology letters · 2021Article
- The three Ts of virulence evolution during zoonotic emergence.Proceedings. Biological sciences · 2021Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The virulence-transmission trade-off hypothesis has provided a dominant theoretical basis for predicting pathogen virulence evolution, but empirical tests are rare, particularly at pathogen emergence. The central prediction of this hypothesis is that pathogen fitness is maximized at intermediate virulence due to a trade-off between infection duration and transmission rate. However, obtaining sufficient numbers of pathogen isolates of contrasting virulence to test the shape of relationships between key pathogen traits, and doing so without the confounds of evolved host protective immunity (as expected at emergence), is challenging. Here, we inoculated 55 isolates of the bacterial pathogen,
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