ReviewNeuro-oncology practice2020
Determining medical decision-making capacity in brain tumor patients: why and how?
Review in Neuro-oncology practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 47 citations in OpenAlex.
- Sexual Dysregulation After Traumatic Brain Injury and Stroke: A Critical Narrative Review of Neurobiology, Clinical Phenotypes, and Management.Brain sciences · 2026Review
- Burden of Respiratory Syncytial Virus in Older ADults in Nagasaki, Japan (Nagasaki ROAD): Preliminary Results (April 2024-March 2025) of a Prospective, Multicenter, Epidemiological Study.Infectious diseases and therapy · 2026Article
- Long-Term Outcomes Associated With Posterior Fossa Syndrome in Survivors of Childhood Medulloblastoma.JAMA network open · 2026Article
- A scoping review: Understanding brain tumor patients' decisional needs and preferences.Neuro-oncology practice · 2025Review
- End-of-life care in patients with glioblastoma after early advance care planning.Neuro-oncology practice · 2025Article
- Early Palliative Care in Patients with Glioblastoma: Co-Design of an Integrated Care Pathway.Healthcare (Basel, Switzerland) · 2025Article
- Shared decision-making in neuro-oncology: Existing practices and future steps.Neuro-oncology practice · 2025Article
- A thematic analysis of shared decision-making in consultations with patients with a presumed brain tumor and neurosurgeons.Neuro-oncology practice · 2025Article
- The relationship between proxy decision-making content and cues by families of patients with malignant brain tumor: A descriptive qualitative study.International journal of nursing sciences · 2025Article
- Prospective assessment of end-of-life symptoms and quality of life in patients with high-grade glioma.Neuro-oncology practice · 2024Article
- Current status of advance care planning, palliative care consultation, and end-of-life care in patients with glioblastoma in South Korea.The oncologist · 2024Article
- Do presenting symptoms predict treatment decisions and survival in glioblastoma? Real-world data from 1458 patients in the Swedish brain tumor registry.Neuro-oncology practice · 2024Article
- Palliative care services in neuro-oncology: Mind the gap.Neuro-oncology practice · 2024Article
- European Association of Neuro-Oncology's 30th anniversary: A successful and growing relationship withNeuro-oncology practice · 2024Article
- Inequalities in access to neuro-oncology supportive care and rehabilitation: A survey of healthcare professionals' perspectives.Neuro-oncology practice · 2024Article
- Predicting Cognitive Functioning for Patients with a High-Grade Glioma: Evaluating Different Representations of Tumor Location in a Common Space.Neuroinformatics · 2024Article
- Cognitive functioning in untreated glioma patients: The limited predictive value of clinical variables.Neuro-oncology · 2024Article
- Large language models as decision aids in neuro-oncology: a review of shared decision-making applications.Journal of cancer research and clinical oncology · 2024Review
- Article
- Advance care planning (ACP) in glioblastoma patients: Evaluation of a disease-specific ACP program and impact on outcomes.Neuro-oncology practice · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 18 institutions in 9 countries.
Funding
Abstract
backgroundBrain tumor patients are at high risk of impaired medical decision-making capacity (MDC), which can be ethically challenging because it limits their ability to give informed consent to medical treatments or participation in research. The European Association of Neuro-Oncology Palliative Care Multidisciplinary Task Force performed a systematic review to identify relevant evidence with respect to MDC that could be used to give recommendations on how to cope with reduced MDC in brain tumor patients.
methodsA literature search in several electronic databases was conducted up to September 2019, including studies with brain tumor and other neurological patients. Information related to the following topics was extracted: tools to measure MDC, consent to treatment or research, predictive patient- and treatment-related factors, surrogate decision making, and interventions to improve MDC.
resultsA total of 138 articles were deemed eligible. Several structured capacity-assessment instruments are available to aid clinical decision making. These instruments revealed a high incidence of impaired MDC both in brain tumors and other neurological diseases for treatment- and research-related decisions. Incapacity appeared to be mostly determined by the level of cognitive impairment. Surrogate decision making should be considered in case a patient lacks capacity, ensuring that the patient's "best interests" and wishes are guaranteed. Several methods are available that may help to enhance patients' consent capacity.
conclusionsClinical recommendations on how to detect and manage reduced MDC in brain tumor patients were formulated, reflecting among others the timing of MDC assessments, methods to enhance patients' consent capacity, and alternative procedures, including surrogate consent.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.