Evidence map›Paper›PMID 33312511›Full record

ReviewJournal of global health2020

The role of children in the transmission of SARS-CoV2: updated rapid review.

Xue Li, Wei Xu, Marshall Dozier, Yazhou He, Amir Kirolos, Zhongyu Lang, Peige Song, Evropi Theodoratou, UNCOVER

Open access · greenAbstract readReview
In one paragraph

Review in Journal of global health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 4 pooled it
1.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 4 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Measures implemented in the school setting to contain the COVID-19 pandemic.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. SARS-CoV-2 Circulation in the School Setting: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022
    Pooled it
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  12. Paediatrics & child health · 2022
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  14. Seroprevalence of SARS-CoV-2 antibodies in front-line pediatric health care workers.Journal of the American College of Emergency Physicians open · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Xue LiSchool of Public Health and the Second Affiliated Hospital, Zhejiang University, Hangzhou, China.
Wei XuCentre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Marshall DozierInformation Services, University of Edinburgh, Edinburgh, United Kingdom.
Yazhou HeCentre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Amir KirolosCentre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Zhongyu LangCentre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Peige SongSchool of Public Health and the Second Affiliated Hospital, Zhejiang University, Hangzhou, China.
Evropi TheodoratouCentre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
UNCOVER
University of Edinburgh · GBSecond Affiliated Hospital of Zhejiang University · CNEdinburgh Cancer Research · GBUniversity of Liverpool · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

backgroundUnderstanding carriage and transmission potential of SARS-CoV-2 in children is of paramount importance to understand the spread of virus in school and community settings.

methodsWe performed an updated rapid review to investigate the role of children in the transmission of SARS-CoV-2. We synthesized evidence for five categories and results are reported narratively.

resultsA total of 33 new studies were included for this review. We did not identify additional studies that reported documented cases of SARS-CoV-2 transmission by children. We identified 15 new studies that demonstrate children's susceptibility and transmission risk of SARS-CoV-2 with evidence provided on the chance of being index or secondary cases, the potential of faecal-oral transmission, and the possibility of asymptomatic transmission. There is little data on the transmission of SARS-CoV-2 in schools. There were three studies reporting COVID-19 school outbreaks in France (Oise), Australia (New South Wales) and Israel. The remaining four studies found that all reported cases did not infect any other pupils or staff. With data from seven studies and governmental websites, the proportion of children among all confirmed COVID-19 patients was estimated for 29 countries, varying from 0.3% (lowest in Spain) up to 13.8% (highest in Argentina). Lastly, we identified seven studies reporting on PIMS-TS linked to COVID-19 among paediatric patients.

conclusionsThere is somewhat limited evidence available for quantifying the extent to which children may contribute to overall transmission, but the balance of evidence so far suggests that children and schools play only a limited role in overall transmission.

Indexed as

AdolescentAge FactorsChildChild, PreschoolCOVID-19Disease OutbreaksFecesFemaleGlobal HealthHumansMaleSARS-CoV-2SchoolsSeroepidemiologic StudiesSystemic Inflammatory Response SyndromeViral Load

Identifiers

PMID33312511
PMCPMC7719356
OpenAlexW3108120552

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.