ArticleAmerican journal of translational research2020
Effects of injectable platelet rich fibrin on bone remodeling in combination with DBBM in maxillary sinus elevation: a randomized preclinical study.
Article in American journal of translational research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 25 citations in OpenAlex.
- Efficacy of injectable platelet-rich fibrin associated with particulated deproteinized bovine bone mineral in horizontal maxillary regeneration - a randomized, triple blinded, split-mouth controlled clinical trial.Clinical oral investigations · 2026Trial
- [Evaluation of the clinical effect of concentrated growth factor combined with sticky bone in maxillary anterior alveolar ridge preservation].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2025Trial
- Article
- Effect of Centrifugation Methods on the Regenerative Potential of Concentrated Platelet-Rich Fibrin: An In Vitro Study.European journal of dentistry · 2026Article
- The efficacy of blood-derived growth factor source compared to bone-derived growth factor source on bone regeneration in critical-sized rabbit calvarial bone defects.BMC oral health · 2026Article
- Hydrogel and Injectable Platelet-Rich Fibrin: A Synergistic Approach to Osteogenesis.European journal of dentistry · 2026Article
- Combined application of a GSK3 inhibitor and injectable platelet rich fibrin with deproteinized bovine bone improves bone regeneration.Scientific reports · 2026Article
- Platelet-Rich Fibrin Low-Speed Centrifugation Protocols and Particulate Bovine Bone on Bone Defects Repair.Brazilian dental journal · 2025Article
- Impact of Infrabony Defects Treatment on Periodontal Markers and Glycated Hemoglobin Using Platelet-Rich Fibrin, Guided Tissue Regeneration, and Access-Flap Surgery.Medicina (Kaunas, Lithuania) · 2024Article
- The effect of injectable platelet-rich fibrin in combination with autogenous bone grafts on bone healing in an ovariectomized osteoporotic rat model with critical-sized defects.Saudi medical journal · 2024Article
- The Interplay of Raloxifene and Sonochemical Bio-Oss in Early Maxillary Sinus Bone Regeneration: A Histological and Immunohistochemical Analysis in Rabbits.Medicina (Kaunas, Lithuania) · 2023Article
- Alveolar Bone Preservation Using a Combination of Nanocrystalline Hydroxyapatite and Injectable Platelet-Rich Fibrin: A Study in Rats.Current issues in molecular biology · 2023Article
- Standardization of Animal Models and Techniques for Platelet-Rich Fibrin Production: A Narrative Review and Guideline.Bioengineering (Basel, Switzerland) · 2023Review
- Effect of local injection of injectable platelet-rich fibrin on bone remodeling during orthodontic tooth movement in dogs.Dental research journal · 2023Article
- Effect of local injection of injectable platelet-rich fibrin on eruption rate of teeth (Rabbit animal model).Journal of orthodontic science · 2023Article
- The application of injectable platelet-rich fibrin in regenerative dentistry: A systematic scoping review ofThe Japanese dental science review · 2022Article
- Effect of Injectable Platelet-Rich Fibrin with a Nano-Hydroxyapatite Bone Graft on the Treatment of a Grade II Furcation Defect.Bioengineering (Basel, Switzerland) · 2022Article
- Evaluation of volume changes following lateral window maxillary sinus floor elevation using Minics software.Annals of translational medicine · 2022Article
- The feasibility of injectable PRF (I-PRF) for bone tissue engineering and its application in oral and maxillofacial reconstruction: From bench to chairside.Biomaterials advances · 2022Review
- Digital Workflow for the Design, Manufacture, and Application of Custom-Made Short Implants With Wing Retention Device.Frontiers in bioengineering and biotechnology · 2022Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study aims to assess the angiogenic and osteogenic capacity in rabbit sinus model grafted with Deproteinized bovine bone mineral (DBBM) particles soaked in injectable Platelet rich fibrin (iPRF), both of which interacted to form an integrated block. MATERIALS AND
methodsAmong sixteen rabbits, bilateral maxillary sinuses were randomly grafted with either DBBM containing iPRF (iPRF+DBBM group), or DBBM alone (DBBM group). After a 4 and 8-week healing period, animals were sacrificed for micro-CT, histological and immunofluorescence analyses, respectively.
resultsNew bone formation in the iPRF+DBBM group was largely observed around the basal bone wall and Schneiderian membrane (SM), which further substitute the bone grafting material in a bidirectional remodeling pattern. Although the ultimate amount of bone volume was of no significant difference between two groups in radiographical image, the expression of ALP and TRAP staining were significantly higher in the experimental group with numerous vascular formations at 4
conclusioniPRF+DBBM accelerated vascular formation, bone remodeling and substitution of bone graft materials at the early healing period, even though it failed to increase the bone volume in a long-term period. This integrated grafting biomaterial will have great potential in the application of sinus augmentation, which provides a favorable environment for early implant placement.
Indexed as
Identifiers
33312369PMC7724338W3116848122What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.