Evidence map›Paper›PMID 33312350›Full record

ReviewAmerican journal of translational research2020

Spermatogonial stem cells are a promising and pluripotent cell source for regenerative medicine.

Zhe Chen, Fan Hong, Zhiyuan Wang, Dingjun Hao, Hao Yang

Open access · greenAbstract readReview
In one paragraph

Review in American journal of translational research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Induced Neurons From Germ Cells inFrontiers in neuroscience · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zhe ChenDepartment of Spine Surgery, Hong Hui Hospital, Xi'an Jiaotong University Xi'an 710054, China.
Fan HongDepartment of Spine Surgery, Hong Hui Hospital, Xi'an Jiaotong University Xi'an 710054, China.
Zhiyuan WangDepartment of Spine Surgery, Hong Hui Hospital, Xi'an Jiaotong University Xi'an 710054, China.
Dingjun HaoDepartment of Spine Surgery, Hong Hui Hospital, Xi'an Jiaotong University Xi'an 710054, China.
Hao YangTranslational Medicine Center, Hong Hui Hospital, Xi'an Jiaotong University Xi'an 710054, China.
Xi'an Jiaotong University · CNXi'an Honghui Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regenerative medicine has been shown to hold enormous potential to treat traumatic and degenerative diseases, and substantial advancements have been made in the recent decades. In particular, different cell types were evaluated in basic research and preclinical studies on cell-based therapy applications. Despite the extraordinary achievements made in experimental studies and clinical practice, a considerable number of obstacles, such as the cellular source, ethical and safety issues, hinder further clinical applications. Spermatogonial stem cells (SSCs) are gradually becoming the research focus of cell-based regenerative medicine owing to their unique merits over other types of stem cells, particularly the lack of ethical concerns and lower immunogenicity. In addition, SSCs have been successfully induced to differentiate into other cell types under different appropriate conditions in compelling studies. Based on these properties, we systemically reviewed the development of SSCs as an attractive cell source for cell-based regenerative medicine.

Indexed as

cell therapydegenerative diseaseregenerative medicineSpermatogonial stem cellstransdifferentiation

Identifiers

PMID33312350
PMCPMC7724348
OpenAlexW3112125748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.