Evidence map›Paper›PMID 33312341›Full record

ArticleOxidative medicine and cellular longevity2020

6,8-Diprenylorobol Induces Apoptosis in Human Hepatocellular Carcinoma Cells via Activation of FOXO3 and Inhibition of CYP2J2.

Chang Min Lee, Jongsung Lee, Su-Nyeong Jang, Jong Cheol Shon, Zhexue Wu, Kyungmoon Park, Kwang-Hyeon Liu, See-Hyoung Park

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
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  7. CYP2J2Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Chang Min LeeDepartment of Bio and Chemical Engineering, Hongik University, Sejong 30016, Republic of Korea.
Jongsung LeeDepartment of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Republic of Korea.
Su-Nyeong JangBK21 Plus KNU Multi-Omics Based Creative Drug Research Team, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.
Jong Cheol ShonBK21 Plus KNU Multi-Omics Based Creative Drug Research Team, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.
Zhexue WuBK21 Plus KNU Multi-Omics Based Creative Drug Research Team, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.
Kyungmoon ParkDepartment of Bio and Chemical Engineering, Hongik University, Sejong 30016, Republic of Korea.ORCID https://orcid.org/0000-0002-8297-3740
Kwang-Hyeon LiuBK21 Plus KNU Multi-Omics Based Creative Drug Research Team, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID https://orcid.org/0000-0002-3285-5594
See-Hyoung ParkDepartment of Bio and Chemical Engineering, Hongik University, Sejong 30016, Republic of Korea.ORCID https://orcid.org/0000-0003-0020-7389
Kyungpook National University · KRHongik University · KRSungkyunkwan University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

6,8-Diprenylorobol is a phytochemical derived from the roots of

Indexed as

Antineoplastic Agents, PhytogenicApoptosisCarcinoma, HepatocellularCytochrome P-450 CYP2J2Cytochrome P-450 Enzyme SystemForkhead Box Protein O3Gene Expression Regulation, EnzymologicGene Expression Regulation, NeoplasticHep G2 CellsHumansLiver NeoplasmsNeoplasm ProteinsAntineoplastic Agents, PhytogenicCYP2J2 protein, humanCytochrome P-450 CYP2J2Cytochrome P-450 Enzyme SystemForkhead Box Protein O3FOXO3 protein, humanNeoplasm Proteins

Identifiers

PMID33312341
PMCPMC7721496
OpenAlexW3109077447

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.