Evidence map›Paper›PMID 33312337›Full record

ReviewOxidative medicine and cellular longevity2020

p53: A Key Protein That Regulates Pulmonary Fibrosis.

Qi Wu, Ke-Jia Zhang, Shi-Min Jiang, Lu Fu, Yue Shi, Ru-Bin Tan, Jie Cui, Yao Zhou

Open access · hybridAbstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 86 citations in OpenAlex.

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  11. Targeted liposomes for macrophages-mediated pulmonary fibrosis therapy.Drug delivery and translational research · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Qi WuDepartment of Physiology, Xuzhou Medical University, Xuzhou 221009, China.ORCID https://orcid.org/0000-0002-0537-6467
Ke-Jia ZhangDepartment of Pathophysiology, Xuzhou Medical University, Xuzhou 221009, China.ORCID https://orcid.org/0000-0002-6970-8571
Shi-Min JiangDepartment of Pathophysiology, Xuzhou Medical University, Xuzhou 221009, China.ORCID https://orcid.org/0000-0002-1795-8587
Lu FuDepartment of Physiology, Xuzhou Medical University, Xuzhou 221009, China.ORCID https://orcid.org/0000-0001-5613-0582
Yue ShiDepartment of Physiology, Xuzhou Medical University, Xuzhou 221009, China.ORCID https://orcid.org/0000-0002-3043-7321
Ru-Bin TanDepartment of Physiology, Xuzhou Medical University, Xuzhou 221009, China.ORCID https://orcid.org/0000-0002-1513-5616
Jie CuiDepartment of Physiology, Xuzhou Medical University, Xuzhou 221009, China.ORCID https://orcid.org/0000-0003-3849-4184
Yao ZhouDepartment of Pathophysiology, Xuzhou Medical University, Xuzhou 221009, China.ORCID https://orcid.org/0000-0002-2845-6339
Xuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary fibrosis is a progressively aggravating lethal disease that is a serious public health concern. Although the incidence of this disease is increasing, there is a lack of effective therapies. In recent years, the pathogenesis of pulmonary fibrosis has become a research hotspot. p53 is a tumor suppressor gene with crucial roles in cell cycle, apoptosis, tumorigenesis, and malignant transformation. Previous studies on p53 have predominantly focused on its role in neoplastic disease. Following in-depth investigation, several studies have linked it to pulmonary fibrosis. This review covers the association between p53 and pulmonary fibrosis, with the aim of providing novel ideas to improve the clinical diagnosis, treatment, and prognosis of pulmonary fibrosis.

Indexed as

Pulmonary FibrosisAnimalsHumansPrognosisTumor Suppressor Protein p53TP53 protein, humanTumor Suppressor Protein p53

Identifiers

PMID33312337
PMCPMC7721501
OpenAlexW3110637768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.