ArticleJournal of human kinetics2020
Genetics of Muscle Stiffness, Muscle Elasticity and Explosive Strength.
Article in Journal of human kinetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Association Between the c.34C > T (rs17602729) Polymorphism of the AMPD1 Gene and the Status of Endurance and Power Athletes: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2025Pooled it
- Candidate gene polymorphisms and power athlete status: a meta-analytical approach.Journal of physiology and biochemistry · 2025Pooled it
- Position dependent elasticity of the anterior talofibular ligament in healthy young women: an in-vivo shear wave elastography study.European journal of applied physiology · 2026Article
- Changes in the mechanical properties and pressure pain thresholds of muscles in patients with fibromyalgia and their relationship with clinical parameters: a case-control study.European journal of applied physiology · 2026Article
- Can MyotonPRO Be Used to Assess the Muscles Surrounding the Shoulder Joint in Patients Who Have Undergone Arthroscopic Rotator Cuff Repair (ARCR) and Reverse Shoulder Arthroplasty (RSA)? A Review of the Current Evidence.Journal of clinical medicine · 2026Review
- Achilles tendon ultrasound-derived properties of the dominant and non-dominant jumping leg of university basketball athletes: relation with performance, range of motion, and injury.Frontiers in sports and active living · 2026Article
- Assessing Congenital Muscular Torticollis Using Myotonometry: A Novel Approach.Journal of musculoskeletal & neuronal interactions · 2025Article
- Experiences of People with Multiple Sclerosis in Sensor-Based Jump Assessment.Bioengineering (Basel, Switzerland) · 2025Article
- The effects of blood flow restriction combined with resistance training on lower limb strength, muscle hypertrophy, jumping ability, and sprint speed in athletes: a systematic review and meta-analysis.Frontiers in physiology · 2025Review
- The Association of Age, Sex, and BMI on Lower Limb Neuromuscular and Muscle Mechanical Function in People with Multiple Sclerosis.Biomedicines · 2024Article
- Article
- Age-related changes and sex differences in ankle plantarflexion velocity.Scientific reports · 2023Observational
- Movement Asymmetries: From Their Molecular Origin to the Analysis of Movement Asymmetries in Athletes.Life (Basel, Switzerland) · 2023Review
- Genetic Variants within NOGGIN, COL1A1, COL5A1, and IGF2 are Associated with Musculoskeletal Injuries in Elite Male Australian Football League Players: A Preliminary Study.Sports medicine - open · 2022Article
- Genetic profiles to identify talents in elite endurance athletes and professional football players.PloS one · 2022Article
- Urinary Titin N-Fragment as a Biomarker of Muscle Atrophy, Intensive Care Unit-Acquired Weakness, and Possible Application for Post-Intensive Care Syndrome.Journal of clinical medicine · 2021Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Muscle stiffness, muscle elasticity and explosive strength are the main components of athletes' performance and they show a sex-based as well as ethnicity variation. Muscle stiffness is thought to be one of the risk factors associated with sports injuries and is less common in females than in males. These observations may be explained by circulating levels of sex hormones and their specific receptors. It has been shown that higher levels of estrogen are associated with lower muscle stiffness responsible for suppression of collagen synthesis. It is thought that these properties, at least in part, depend on genetic factors. Particularly, the gene encoding estrogen receptor 1 (ESR1) is one of the candidates that may be associated with muscle stiffness. Muscle elasticity increases with aging and there is evidence suggesting that titin (encoded by the TTN gene), a protein that is expressed in cardiac and skeletal muscles, is one of the factors responsible for elastic properties of the muscles. Mutations in the TTN gene result in some types of muscular dystrophy or cardiomyopathy. In this context, TTN may be regarded as a promising candidate for studying the elastic properties of muscles in athletes. The physiological background of explosive strength depends not only on the muscle architecture and muscle fiber composition, but also on the central nervous system and functionality of neuromuscular units. These properties are, at least partly, genetically determined. In this context, the ACTN3 gene code for α-actinin 3 has been widely researched.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.