ArticleJournal of human kinetics2020
The Effects of Low-Load Vs. High-Load Resistance Training on Muscle Fiber Hypertrophy: A Meta-Analysis.
Article in Journal of human kinetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Heavy or light: is muscle fiber growth load-specific? A systematic review and meta-regression.Frontiers in physiology · 2026Pooled it
- The effects of French contrast training on lower limb athletic performance in healthy adults: a systematic review and meta-analysis.Frontiers in physiology · 2025Pooled it
- The influence of resistance exercise training prescription variables on skeletal muscle mass, strength, and physical function in healthy adults: An umbrella review.Journal of sport and health science · 2024Pooled it
- Preferred Reporting Items for Resistance Exercise Studies (PRIRES): A Checklist Developed Using an Umbrella Review of Systematic Reviews.Sports medicine - open · 2023Pooled it
- Resistance training prescription for muscle strength and hypertrophy in healthy adults: a systematic review and Bayesian network meta-analysis.British journal of sports medicine · 2023Pooled it
- Effects of Resistance Training Performed with Different Loads in Untrained and Trained Male Adult Individuals on Maximal Strength and Muscle Hypertrophy: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Exploring the relationship between lower-limb strength and neuromuscular activation in running: Insights from integrated EMG.iScience · 2026Article
- American College of Sports Medicine Position Stand. Resistance Training Prescription for Muscle Function, Hypertrophy, and Physical Performance in Healthy Adults: An Overview of Reviews.Medicine and science in sports and exercise · 2026 · on this mapReview
- Do Flywheel Exercises Provide Eccentric-Overload Training?Sports medicine - open · 2026Article
- Training Practices Among Spanish Natural Elite Bodybuilders in the Pre-Contest Phase.Sports (Basel, Switzerland) · 2026Article
- Instability resistance training in collegiate basketball: a multitheoretical experimental study.Frontiers in sports and active living · 2026Article
- Muscle Hypertrophy, Strength, and Salivary Hormone Changes Following 9 Weeks of High- or Low-Load Resistance Training.Journal of functional morphology and kinesiology · 2025Article
- Integration of resistance exercise into a multimodal approach to prehabilitation for patients with sarcopenia prior to surgery: a narrative review.Frontiers in rehabilitation sciences · 2025Review
- Skeletal muscle adaptations to high-intensity, low-volume concurrent resistance and interval training in recreationally active men and women.Physiological reports · 2024Article
- Effect of free-weight vs. machine-based strength training on maximal strength, hypertrophy and jump performance - a systematic review and meta-analysis.BMC sports science, medicine & rehabilitation · 2023Article
- Fiber-Type-Specific Hypertrophy with the Use of Low-Load Blood Flow Restriction Resistance Training: A Systematic Review.Journal of functional morphology and kinesiology · 2023Review
- The Effects of Accessory Blood Flow Restriction Training on Muscle Size and Strength in Division III Soccer Athletes: A Preliminary Ecological Study.International journal of exercise science · 2023Article
- Obesity Pillars Roundtable: Body mass index and body composition in Black and Female individuals. Race-relevant or racist? Sex-relevant or sexist?Obesity pillars · 2022Article
- Appropriate Reporting of Exercise Variables in Resistance Training Protocols: Much more than Load and Number of Repetitions.Sports medicine - open · 2022Review
- Strength Training in Swimming.International journal of environmental research and public health · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this meta-analysis was to explore the effects of low-load vs. high-load resistance training on type I and type II muscle fiber hypertrophy. Searches for studies were performed through ten databases. Studies were included if they: (a) compared the effects of low-load vs. high-load resistance training (performed to momentary muscular failure); and, (b) assessed muscle fiber hypertrophy. A random-effects meta-analysis was performed to analyze the data. Ten study groups were included in the analysis. In the meta-analysis for the effects of low-load vs. high-load resistance training on type I muscle fiber hypertrophy, there was no significant difference between the training conditions (standardized mean difference: 0.28; 95% confidence interval: -0.27, 0.82; p = 0.316; I
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.