Evidence map›Paper›PMID 33312179›Full record

ArticleFrontiers in immunology2020

Type II Natural Killer T Cells Contribute to Protection Against Systemic Methicillin-Resistant

Samantha Genardi, Lavanya Visvabharathy, Liang Cao, Eva Morgun, Yongyong Cui, Chao Qi, Yi-Hua Chen, Laurent Gapin, Evgeny Berdyshev, Chyung-Ru Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Research progress on T-cell responses inFrontiers in microbiology · 2026
    Pooled it
  2. Pathogens (Basel, Switzerland) · 2025
    Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Genetic Analysis of iNKT Cell Development and Function.Methods in molecular biology (Clifton, N.J.) · 2021
    Review
  11. Article
  12. Article
  13. NKT Cells Contribute to the Control of Microbial Infections.Frontiers in cellular and infection microbiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Samantha GenardiDepartment of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Lavanya VisvabharathyDepartment of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Liang CaoDepartment of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Eva MorgunDepartment of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Yongyong CuiDepartment of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Chao QiDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Yi-Hua ChenDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Laurent GapinDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, United States.
Evgeny BerdyshevDepartment of Medicine, National Jewish Health, Denver, CO, United States.
Chyung-Ru WangDepartment of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Northwestern University · USUniversity of Colorado Denver · US

Funding

The Role of Group 1 CD1-restricted T Cells in Infectious DiseaseR01AI057460 · NIAID · UNIVERSITY OF CHICAGO · PI WANG, CHYUNG-RU · 2004 to 2020
$5.7M
TCR signal strength and iNKT cell subset developmentR01AI130198 · NIAID · UNIVERSITY OF COLORADO DENVER · PI GAPIN, LAURENT · 2018 to 2022
$1.9M
NIAID NIH HHS R01 AI057460NIAID NIH HHS R01 AI130198
6 · The paper itself

Abstract

Methicillin-resistant

Indexed as

Immunity, CellularAdoptive TransferAdultAgedAnimalsAntigens, CD1dBacterial LoadCase-Control StudiesCell ProliferationCells, CulturedDisease Models, AnimalFemaleHistocompatibility Antigens Class IIHost-Pathogen InteractionsHumansInterferon-gammaAntigens, CD1dCD1d antigen, mouseHistocompatibility Antigens Class IIIFNG protein, mouseInterferon-gammaInterleukin-12Myd88 protein, mouseMyeloid Differentiation Factor 88Receptors, Antigen, T-CellCD1cytokineknockout micelipid antigensnatural killer T cellsStaphylococcus aureus

Identifiers

PMID33312179
PMCPMC7708336
OpenAlexW3104065528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.