Evidence map›Paper›PMID 33312065›Full record

ArticleJournal of medical biochemistry2020

Inflammatory markers in end-stage renal disease patients on haemodialysis.

Phebe Lotfy Abdel-Messeih, Manal Mohamed Alkady, Neveen Mostafa Nosseir, Mohamed Said Tawfik

2 registry-linked trialsOpen access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06064708 nacompletednot on this mapstarted 2023, after this paper: background citation

The Impact of Mindfulness-Based Intervention on Psychophysical Health in Patients Undergoing Hemodialysis: An Experimental Study

TypeinterventionalSponsorJordan University of Science and TechnologyRan2023 to 2023Enrolled64ConditionsEnd Stage Renal DiseaseArmsMindfulness-based intervention
NCT06936293 nacompletednot on this mapstarted 2024, after this paper: background citation

Effects of Mindfulness Meditation on Quality of Sleep, Perceived Stress, Serum Cortisol, and C-reactive Protein in Hemodialysis Patients

TypeinterventionalSponsorUniversity of JordanRan2024 to 2025Enrolled56ConditionsEnd-Stage Renal Disease, Hemodialysis ComplicationArmsMindfulness Meditation
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Phebe Lotfy Abdel-MesseihEgyptian Atomic Energy Authority (EAEA), National Centers for Radiation Research and Technology (NCRRT), Health Radiation Research Department, Clinical Pathology Unit, Egypt.
Manal Mohamed AlkadyEgyptian Atomic Energy Authority (EAEA), National Centers for Radiation Research and Technology (NCRRT), Health Radiation Research Department, Clinical Pathology Unit, Egypt.
Neveen Mostafa NosseirEgyptian Atomic Energy Authority (EAEA), National Centers for Radiation Research and Technology (NCRRT), Health Radiation Research Department, Clinical Pathology Unit, Egypt.
Mohamed Said TawfikEgyptian Atomic Energy Authority (EAEA), National Centers for Radiation Research and Technology (NCRRT), Health Radiation Research Department, Internal Medicine Unit, Cairo, Egypt.
Egyptian Atomic Energy Authority · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCXC chemokine ligand 16 (CXCL16) is an inflammatory chemokine that mediates renal infiltration of macrophages and activated T cells. Aim: To investigate serum levels of CXCL16 in patients undergoing hemodialysis and their correlation with other inflammatory markers such as C-reactive protein (CRP) and intact parathyroid hormone (iPTH).

methodsThe study included 40 hemodialysis patients (22 males) and 40 age and gender-matched controls (24 males). Fasting blood sugar (FBS), urea, creatinine, calcium and inorganic phosphorous were assayed in participants using routine methods, glycosylated hemoglobin (HbA1c) by quantitative chromatographic spectrophotometry, iPTH by chemiluminescent microparticle immunoassay, CRP by nephelometry and CXCL16 by ELISA technique.

resultsSerum CXCL16, CRP, PTH, FBS, HbA1c, phosphorus, urea, and creatinine levels were significantly higher in hemodialysis patients compared to controls (p<0.00001). No statistically significant differences were observed between patients and controls for calcium. Serum CXCL16 levels correlated positively with CRP (r=0.956, p<0.00001) and iPTH (r=-0.403, p<0.001). Hemodialysis patients (diabetics or hypertensives) had significantly higher CXCL16 levels compared to non-diabetics or non-hypertensives.

conclusionsHigh levels of serum CXCL16, CRP and iPTH reflect the inflammatory status of hemodialysis patients and help avoid complications. Serum CXCL16 could be used as a biomarker together with CRP in these patients.

Indexed as

CRPCXCL16ESRDiPTH

Identifiers

PMID33312065
PMCPMC7710380
OpenAlexW3017266745

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.