Bilateral Adnexal Masses in a Young Female: Rare Presentation of Hepatocellular Carcinoma With Review of the Literature.

Kapatia Gargi, Gupta Parikshaa, Pradip K Saha, Mehtani Rohit, Premkumar Madhumita, Arvind Rajvanshi

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In one paragraph

Article in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Kapatia GargiDepartment of Cytology and Gynecologic Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh.

Gupta ParikshaaDepartment of Cytology and Gynecologic Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh.

Pradip K SahaDepartment of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research, Chandigarh.

Mehtani RohitDepartment of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh.

Premkumar MadhumitaDepartment of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh.

Arvind RajvanshiDepartment of Cytology and Gynecologic Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovaries are a common niche for metastasis. Metastatic malignancies account for 5-30% of all ovarian malignancies. Hepatocellular carcinoma (HCC) is one of the rare malignancies to metastasize to the ovaries. Of all the variants of HCC, fibrolamellar HCC (FLHCC) variant is extremely uncommon and accounts for around 1% of all HCC cases. FLHCC metastasizing to ovaries, at presentation, is an exceptional occurrence. We present a case of a young female who presented with bilateral adnexal masses and was diagnosed as metastatic FLHCC on histopathological examination and confirmed by immunohistochemistry. In addition, a thorough literature review highlighting the previously reported cases is also presented.

Indexed as

AFP, Alpha-fetoproteinALT, Alanine aminotransferaseAST, Aspartate aminotransferaseCA-125, Cancer antigen-125CA19-9, Cancer antigen 19-9CD68, Cluster differentiation 68CEA, Carcinoembryonic antigenCK19, Cytokeratin 19CK7, Cytokeratin-7CT, Computerized tomographyfibrolamellar carcinomafibrolamellar variantFLHCC, Fibrolamellar hepatocellular carcinomaHBsAg, Hepatitis B surface antigenHCC, Hepatocellular carcinomaHCV, Hepatitis C virushepatocellular carcinomaHepPar-1, Hepatocyte paraffin antigen-1HIV, Human Immunodeficiency virusKrukenberg tumorovarian metastasisPAX8, Paired box gene 8

Identifiers

PMID33311899

DOI10.1016/j.jceh.2020.01.002

PMCPMC7719967

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