Evidence map›Paper›PMID 33311798›Full record

ArticleNagoya journal of medical science2020

Male infertility treatment for cancer survivors: does anticancer treatment affect infertility treatment?

Hatsuki Hibi, Miho Sugie, Tadashi Ohori, Noritaka Fukunaga, Megumi Sonohara, Yoshimasa Asada

Open access · greenAbstract read
In one paragraph

Article in Nagoya journal of medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hatsuki HibiDepartment of Urology, Kyoritsu General Hospital, Nagoya, Japan.
Miho SugieDepartment of Urology, Kyoritsu General Hospital, Nagoya, Japan.
Tadashi OhoriDepartment of Urology, Kyoritsu General Hospital, Nagoya, Japan.
Noritaka FukunagaAsada Ladies Clinic, Nagoya, Japan.
Megumi SonoharaAsada Ladies Clinic, Nagoya, Japan.
Yoshimasa AsadaAsada Ladies Clinic, Nagoya, Japan.
Iwaki Kyoritsu General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the impact of prior anticancer treatments such as chemotherapy and radiotherapy on subsequent infertility treatment in cancer survivors who consulted our male infertility division. Of 1,525 male infertility patients who consulted our division between 2008 and 2018, 56 (3.7%) were cancer survivors. Of these, 32 received anticancer treatment (group A) and 24 were treated with surgery alone or were seen before anticancer treatment (group B). Semen analysis revealed that azoospermia in 26 subjects (81.3%) and 14 (58.3%) in groups A and B respectively. Ejaculatory dysfunction was observed 1 in group A and in 2 group B subjects. Sperm cryopreservation before anticancer treatment was performed 4 subjects. Sperm retrieval surgery for intracytoplasmic sperm injection (ICSI) was performed in 13 cases in group A and 10 in group B. Motile sperm were recovered in 7 subjects and in 8 subjects in group A and B respectively. Overall pregnancies and deliveries with ICSI were achieved for 7 subjects (21.9%) in group A, and 9 (37.5%) in group B. Successful sperm retrieval may not be affected by prior anticancer treatment as shown in this study. However, some patients abandoned infertility treatment due to the cost of testing and sperm retrieval surgery. Support for the cost of infertility treatment in cancer survivors is necessary.

Indexed as

Antineoplastic AgentsInfertility, MaleRadiotherapySpermatozoaSperm RetrievalAdultCancer SurvivorsCosts and Cost AnalysisCryopreservationFertility PreservationHumansJapanMaleNeeds AssessmentNeoplasmsAntineoplastic Agentsanti-cancer treatmentcancer survivorICSI outcomemale infertilitysperm retrieval surgery

Identifiers

PMID33311798
PMCPMC7719443
OpenAlexW3116632551

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.