Evidence map›Paper›PMID 33311565›Full record

Trial reportScientific reports2020

Automatic recognition of murmurs of ventricular septal defect using convolutional recurrent neural networks with temporal attentive pooling.

Jou-Kou Wang, Yun-Fan Chang, Kun-Hsi Tsai, Wei-Chien Wang, Chang-Yen Tsai, Chui-Hsuan Cheng, Yu Tsao

Abstract readClinical Trial
In one paragraph

Trial report in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A review on deep learning methods for heart sound signal analysis.Frontiers in artificial intelligence · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jou-Kou WangNational Taiwan University Children's Hospital, Taipei, Taiwan.
Yun-Fan ChangiMediPlus Inc., Hsinchu, Taiwan.
Kun-Hsi TsaiiMediPlus Inc., Hsinchu, Taiwan.
Wei-Chien WangiMediPlus Inc., Hsinchu, Taiwan.
Chang-Yen TsaiiMediPlus Inc., Hsinchu, Taiwan.
Chui-Hsuan ChengiMediPlus Inc., Hsinchu, Taiwan.
Yu TsaoResearch Center for Information Technology Innovation at Academia Sinica, Taipei, Taiwan. yu.tsao@citi.sinica.edu.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recognizing specific heart sound patterns is important for the diagnosis of structural heart diseases. However, the correct recognition of heart murmur depends largely on clinical experience. Accurately identifying abnormal heart sound patterns is challenging for young and inexperienced clinicians. This study is aimed at the development of a novel algorithm that can automatically recognize systolic murmurs in patients with ventricular septal defects (VSDs). Heart sounds from 51 subjects with VSDs and 25 subjects without a significant heart malformation were obtained in this study. Subsequently, the soundtracks were divided into different training and testing sets to establish the recognition system and evaluate the performance. The automatic murmur recognition system was based on a novel temporal attentive pooling-convolutional recurrent neural network (TAP-CRNN) model. On analyzing the performance using the test data that comprised 178 VSD heart sounds and 60 normal heart sounds, a sensitivity rate of 96.0% was obtained along with a specificity of 96.7%. When analyzing the heart sounds recorded in the second aortic and tricuspid areas, both the sensitivity and specificity were 100%. We demonstrated that the proposed TAP-CRNN system can accurately recognize the systolic murmurs of VSD patients, showing promising potential for the development of software for classifying the heart murmurs of several other structural heart diseases.

Indexed as

Heart AuscultationHeart Defects, CongenitalHeart MurmursModels, CardiovascularNeural Networks, ComputerSignal Processing, Computer-AssistedSoftwareAdolescentAdultChildChild, PreschoolFemaleHumansMale

Identifiers

PMID33311565
PMCPMC7732853

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.