Evidence map›Paper›PMID 33311441›Full record

ArticleCell death & disease2020

The plasminogen receptor, Plg-R

Lina Ny, Robert J Parmer, Yue Shen, Sandra Holmberg, Nagyung Baik, Assar Bäckman, Jessica Broden, Malgorzata Wilczynska, Tor Ny, Lindsey A Miles

Open access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Macrophage Plg-RJournal of thrombosis and haemostasis : JTH · 2026
    Article
  5. Article
  6. Journal of inflammation research · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Plasminogen Receptors and Fibrinolysis.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Lina NyDepartment of Medical Biochemistry and Biophysics, Umeå University, 90187, Umeå, Sweden.
Robert J ParmerDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Yue ShenDepartment of Medical Biochemistry and Biophysics, Umeå University, 90187, Umeå, Sweden.
Sandra HolmbergOmnio AB Tvistevägen 48, 90736, Umeå, Sweden.
Nagyung BaikDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.
Assar BäckmanOmnio AB Tvistevägen 48, 90736, Umeå, Sweden.
Jessica BrodenOmnio AB Tvistevägen 48, 90736, Umeå, Sweden.
Malgorzata WilczynskaDepartment of Medical Biochemistry and Biophysics, Umeå University, 90187, Umeå, Sweden.
Tor NyDepartment of Medical Biochemistry and Biophysics, Umeå University, 90187, Umeå, Sweden.
Lindsey A MilesDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA. lmiles@scripps.edu.ORCID 0000-0002-0368-0895
Umeå University · SEScripps Research Institute · USUniversity of California San Diego · US

Funding

Regulation of plasminogen-dependent cell functions by the novel receptor, Plg-RKTR01HL081046 · NHLBI · SCRIPPS RESEARCH INSTITUTE, THE · PI MILES, LINDSEY A · 2007 to 2024
$8.7M
A Novel Plasminogen Receptor Promotes Adipose Function and Metabolic HomeostasisR01HL149511 · NHLBI · SCRIPPS RESEARCH INSTITUTE, THE · PI MILES, LINDSEY A, PARMER, ROBERT J · 2019 to 2022
$3.0M
Regulation of Renal Injury and Fibrosis by the Plasminogen Receptor, Plg-RKTI01BX003933 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI PARMER, ROBERT J · 2018 to 2021
–
BLRD VA I01 BX003933NHLBI NIH HHS R01 HL081046NHLBI NIH HHS R01 HL149511
6 · The paper itself

Abstract

Wound healing is a complex physiologic process that proceeds in overlapping, sequential steps. Plasminogen promotes fibrinolysis and potentiates the inflammatory response during wound healing. We have tested the hypothesis that the novel plasminogen receptor, Plg-R

Indexed as

FibrinolysisWound HealingAnimalsBurnsCell ProliferationEpidermisFibrinogenGene DeletionGene Expression RegulationHeterozygoteInflammationKeratinocytesMice, Inbred C57BLPlasminogenReceptors, Cell SurfaceSkinFibrinogenPlasminogenPLG-R(KT) protein, mouseReceptors, Cell Surface

Identifiers

PMID33311441
PMCPMC7733490
OpenAlexW3112797799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.