Evidence map›Paper›PMID 33311017›Full record

ArticleCerebrovascular diseases (Basel, Switzerland)2021

Impact of COVID-19 Pandemic on a Regional Stroke Thrombectomy Service in the United Kingdom.

Joseph Kwan, Madison Brown, Paul Bentley, Zoe Brown, Lucio D'Anna, Charles Hall, Omid Halse, Sohaa Jamil, Harri Jenkins, Dheeraj Kalladka and 7 more

Abstract read
In one paragraph

Article in Cerebrovascular diseases (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Neurological Complications of COVID-19 in the Elderly.Neuroscience and behavioral physiology · 2022
    Article
  9. Article
  10. Mechanical thrombectomy (MT) for acute ischemic stroke (AIS) in COVID-19 pandemic: a systematic review.The Egyptian journal of neurology, psychiatry and neurosurgery · 2021
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Joseph KwanDepartment of Stroke Medicine, Imperial College London NHS Healthcare Trust, London, United Kingdom, joseph.kwan@nhs.net.
Madison BrownDepartment of Stroke Medicine, Imperial College London NHS Healthcare Trust, London, United Kingdom.
Paul BentleyDepartment of Stroke Medicine, Imperial College London NHS Healthcare Trust, London, United Kingdom.
Zoe BrownDepartment of Stroke Medicine, Imperial College London NHS Healthcare Trust, London, United Kingdom.
Lucio D'AnnaDepartment of Stroke Medicine, Imperial College London NHS Healthcare Trust, London, United Kingdom.
Charles HallImaging Department, Imperial College London NHS Healthcare Trust, London, United Kingdom.
Omid HalseDepartment of Stroke Medicine, Imperial College London NHS Healthcare Trust, London, United Kingdom.
Sohaa JamilDepartment of Stroke Medicine, Imperial College London NHS Healthcare Trust, London, United Kingdom.
Harri JenkinsDepartment of Stroke Medicine, Imperial College London NHS Healthcare Trust, London, United Kingdom.
Dheeraj KalladkaDepartment of Stroke Medicine, Imperial College London NHS Healthcare Trust, London, United Kingdom.
Maneesh PatelImaging Department, Imperial College London NHS Healthcare Trust, London, United Kingdom.
Neil RaneImaging Department, Imperial College London NHS Healthcare Trust, London, United Kingdom.
Abhinav SinghImaging Department, Imperial College London NHS Healthcare Trust, London, United Kingdom.
Eleanor TaylorDepartment of Stroke Medicine, Imperial College London NHS Healthcare Trust, London, United Kingdom.
Marius VenterDepartment of Stroke Medicine, Imperial College London NHS Healthcare Trust, London, United Kingdom.
LobotesisDepartment of Brain Sciences, Imperial College London, Hammersmith Hospital, London, United Kingdom.
Soma BanerjeeDepartment of Stroke Medicine, Imperial College London NHS Healthcare Trust, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe examined the impact of the coronavirus disease 2019 (COVID-19) pandemic on our regional stroke thrombectomy service in the UK.

methodsThis was a single-center health service evaluation. We began testing for COVID-19 on 3 March and introduced a modified "COVID Stroke Thrombectomy Pathway" on 18 March. We analyzed the clinical, procedural and outcome data for 61 consecutive stroke thrombectomy patients between 1 January and 30 April. We compared the data for January and February ("pre-COVID," n = 33) versus March and April ("during COVID," n = 28).

resultsPatient demographics were similar between the 2 groups (mean age 71 ± 12.8 years, 39% female). During the COVID-19 pandemic, (a) total stroke admissions fell by 17% but the thrombectomy rate was maintained at 20% of ischemic strokes; (b) successful recanalization rate was maintained at 81%; (c) early neurological outcomes (neurological improvement following thrombectomy and inpatient mortality) were not significantly different; (d) use of general anesthesia fell significantly from 85 to 32% as intended; and (e) time intervals from onset to arrival, groin puncture, and recanalization were not significantly different, whereas internal delays for external referrals significantly improved for door-to-groin puncture (48 [interquartile range (IQR) 39-57] vs. 33 [IQR 27-44] minutes, p = 0.013) and door-to-recanalization (82.5 [IQR 61-110] vs. 60 [IQR 55-70] minutes, p = 0.018).

conclusionThe COVID-19 pandemic has had a negative impact on the stroke admission numbers but not stroke thrombectomy rate, successful recanalization rate, or early neurological outcome. Internal delays actually improved during the COVID-19 pandemic. Further studies should examine the effects of the COVID-19 pandemic on longer term outcome.

Indexed as

ThrombectomyThrombolytic TherapyAgedAged, 80 and overBrain IschemiaCOVID-19COVID-19 TestingFemaleHospitalizationHumansMaleMiddle AgedSARS-CoV-2StrokeTime-to-TreatmentUnited KingdomCoronavirusCoronavirus disease 2019Health servicePandemicStrokeThrombectomy

Identifiers

PMID33311017
PMCPMC7801959

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.