Evidence map›Paper›PMID 33310881›Full record

ArticleImmunoHorizons2020

RIPK1 Distinctly Regulates

R K Subbarao Malireddi, Sannula Kesavardhana, Rajendra Karki, Balabhaskararao Kancharana, Amanda R Burton, Thirumala-Devi Kanneganti

Open access · goldAbstract read
In one paragraph

Article in ImmunoHorizons, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 152 papers.

0numbers the graph read from it
0cells of the map it votes in
152citing papers in PubMed
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

152 citing papers in PubMed, 188 citations in OpenAlex.

  1. Review
  2. The gasdermin family: from pyroptosis mechanisms to therapeutic targets.Signal transduction and targeted therapy · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. PANoptosis and Immune Remodeling in the Tumor Microenvironment.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Review
  9. Review
  10. Review
  11. Review
  12. Pyroptosis: Molecular mechanisms and function.Journal of physiology and biochemistry · 2026
    Review
  13. Article
  14. WNT4 reprograms dental pulp stem cells to resist PANoptosis and rebuild neurogenic potential for facial nerve injury repair.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Article
  15. Article
  16. Article
  17. Role of PANoptosis in intestinal diseases and its therapeutic implications.Journal of molecular medicine (Berlin, Germany) · 2026
    Review
  18. Article
  19. Research progress on PANoptosis in diabetic cardiomyopathy.Journal of physiology and biochemistry · 2026
    Review
  20. Article

92 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

R K Subbarao MalireddiDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105.
Sannula KesavardhanaDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105.
Rajendra KarkiDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105.
Balabhaskararao KancharanaDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105.
Amanda R BurtonDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105.
Thirumala-Devi KannegantiDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105 thirumala-devi.kanneganti@stjude.org.ORCID 0000-0002-6395-6443
St. Jude Children's Research Hospital · US

Funding

Innate immune sensors, inflammasomes, and inflammasome-mediated processes in cancerR35CA253095 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Thirumala-Devi Kanneganti · 2020 to 2026
$7.0M
Role of NLR Inflammasomes in Autoinflammatory Diseases and Host DefenseR01AR056296 · NIAMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI KANNEGANTI, THIRUMALA-DEVI · 2008 to 2022
$5.9M
The Non-Inflammasome NLRs in Immunity and Host defenseR01AI124346 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Thirumala-Devi Kanneganti · 2016 to 2026
$5.8M
Inflammatory Caspases in Innate Immunity and InflammationR37AI101935 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Thirumala-Devi Kanneganti · 2017 to 2026
$4.9M
Inflammatory Caspases in Innate Immunity and InflammationR01AI101935 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI KANNEGANTI, THIRUMALA-DEVI · 2012 to 2016
$2.2M
NCI NIH HHS R35 CA253095NIAID NIH HHS R01 AI101935NIAID NIH HHS R01 AI124346NIAID NIH HHS R37 AI101935NIAMS NIH HHS R01 AR056296
6 · The paper itself

Abstract

Bacterial pathogens from the genus

Indexed as

NecroptosisPyroptosisAnimalsInflammasomesInflammationMacrophagesMiceMice, Inbred C57BLReceptor-Interacting Protein Serine-Threonine KinasesSignal TransductionYersinia pseudotuberculosisInflammasomesReceptor-Interacting Protein Serine-Threonine KinasesRipk1 protein, mouse

Identifiers

PMID33310881
PMCPMC7906112
OpenAlexW3110985405

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.