Evidence map›Paper›PMID 33310705›Full record

ArticleThe Journal of biological chemistry

Allostery in the nitric oxide dioxygenase mechanism of flavohemoglobin.

Anne M Gardner, Paul R Gardner

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Anne M GardnerResearch and Development Division, Miami Valley Biotech, Dayton, Ohio, USA; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Paul R GardnerResearch and Development Division, Miami Valley Biotech, Dayton, Ohio, USA; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA; Chemistry and Biochemistry Department, University of Dayton, Dayton, Ohio, USA. Electronic address: paul.gardner@mvbiotech.com.
Cincinnati Children's Hospital Medical Center · USUniversity of Dayton · US

Funding

Flavohemoglobin-catalyzed nitric oxide dioxygenationR01GM065090 · NIGMS · CHILDREN'S HOSPITAL MED CTR (CINCINNATI) · PI GARDNER, PAUL R · 2001 to 2005
$952k
NIGMS NIH HHS R01 GM065090
6 · The paper itself

Abstract

The substrates O

Indexed as

Allosteric RegulationDihydropteridine ReductaseEscherichia coliEscherichia coli InfectionsEscherichia coli ProteinsHumansModels, MolecularNADH, NADPH OxidoreductasesNitric OxideOxygenasesProtein ConformationDihydropteridine ReductaseEscherichia coli Proteinshmp protein, E coliNADH, NADPH OxidoreductasesNitric Oxidenitric oxide dioxygenaseOxygenasesallosteryelectron transferflavinflavohemoglobinhemehemoglobinmyoglobinnitric oxidenitric oxide dioxygenaseoxygen

Identifiers

PMID33310705
PMCPMC7948479
OpenAlexW3112812882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.