ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2021
Expanding our understanding of sensory gating in children with autism spectrum disorders.
Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05480605 (Characterizing Occupational Therapy Intervention for Children With Autism Spectrum), which is not on this map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Characterizing Occupational Therapy Intervention for Children With Autism Spectrum
Who cites it
15 citing papers in PubMed, 31 citations in OpenAlex.
- Neural mechanism of Shugan Jieyu combined with zolpidem in insomnia disorder with depressive symptoms: evidence from event-related potentials in Go/No-Go and psychomotor vigilance task.BMC psychiatry · 2026Trial
- Neurologic dance training and home exercise improve motor-cognitive dual-task function similarly, but through potentially different mechanisms, among breast cancer survivors with chemotherapy-induced neuropathy: Initial results of a randomized, controlled clinical trial.Journal of Alzheimer's disease : JAD · 2025Trial
- Magnetoencephalography in human neuroscience research: planning, piloting, implementation and quality assurance.Nature protocols · 2026Review
- Comparative study of ERP habituation to tones and fearful vocalizations in autism spectrum disorders: a translational biomarker for sensory hypersensitivity.Molecular psychiatry · 2026Article
- Temporal Dynamics of Auditory Evoked Neural Oscillations Under a Paired-Pulse Suppression Paradigm.Brain sciences · 2026Article
- Review
- Oscillatory and evoked neural responses underlying gating in the primary somatosensory cortices: Evidence from optically-pumped magnetometry.NeuroImage · 2025Article
- Phenotypic variation in neural sensory processing by deletion size, age, and sex in Phelan-McDermid syndrome.Journal of neurodevelopmental disorders · 2025Article
- Behavioral and neural interrelationships of sensory difficulties, intolerance of uncertainty, and anxiety in autistic children.Research in autism · 2025Article
- Auditory gating and its clinical correlates in adults with chronic tic disorder and neurotypical adults.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024Article
- The Effect of Attention on Auditory Processing in Adults on the Autism Spectrum.Journal of autism and developmental disorders · 2024Article
- Sensory Gating in Neurodevelopmental Disorders: A Scoping Review.Research on child and adolescent psychopathology · 2023Article
- Somatosensory gating is related to behavioral and verbal outcomes in children with mild-to-severe hearing loss.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Comparative Analysis of Dopaminergic and Cholinergic Mechanisms of Sensory and Sensorimotor Gating in Healthy Individuals and in Patients With Schizophrenia.Frontiers in behavioral neuroscience · 2022Review
- Auditory Sensory Gating in Children With Cochlear Implants: A P50-N100-P200 Study.Frontiers in neuroscience · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
objectiveThis study examined sensory gating in children with autism spectrum disorders (ASD). Gating is usually examined at the P50 component and rarely at mid- and late-latency components.
methodsElectroencephalography data were recorded during a paired-click paradigm, from 18 children with ASD (5-12 years), and 18 typically-developing (TD) children. Gating was assessed at the P50, N1, P2, and N2 event-related potential components. Parents of all participants completed the Short Sensory Profile (SSP).
resultsTD children showed gating at all components while children with ASD showed gating only at P2 and N2. Compared to TD children, the ASD group showed significantly reduced gating at P50, N1, and P2. No group differences were found at N2, suggesting typical N2 gating in the ASD group. Time-frequency analyses showed reduced orientation and neural synchronization of auditory stimuli. P50 and N1 gating significantly correlated with the SSP.
conclusionAlthough children with ASD have impaired early orientation and filtering of auditory stimuli, they exhibited gating at P2 and N2 components suggesting use of different gating mechanisms compared to TD children. Sensory deficits in ASD may relate to gating. SIGNIFICANCE: The data provide novel evidence for impaired neural orientation, filtering, and synchronization in children with ASD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.