Evidence map›Paper›PMID 33309700›Full record

ReviewBiochimica et biophysica acta. Biomembranes2021

Amyloid β, α-synuclein and the c subunit of the ATP synthase: Can these peptides reveal an amyloidogenic pathway of the permeability transition pore?

Giuseppe F Amodeo, Evgeny V Pavlov

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biochimica et biophysica acta. Biomembranes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Inorganic Polyphosphate in Mitochondrial Energy Metabolism and Pathology.Progress in molecular and subcellular biology · 2022
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Giuseppe F AmodeoDepartment of Molecular Pathobiology, New York University, United States of America. Electronic address: gfa2112@cumc.columbia.edu.
Evgeny V PavlovDepartment of Molecular Pathobiology, New York University, United States of America. Electronic address: Ep37@nyu.edu.
New York University · US

Funding

Molecular composition of the mitochondrial permeability transition poreR01GM115570 · NIGMS · NEW YORK UNIVERSITY · PI PAVLOV, EVGENY · 2016 to 2020
$1.8M
NIGMS NIH HHS R01 GM115570
6 · The paper itself

Abstract

Mitochondrial Permeability Transition (PT) is a phenomenon of increased permeability of the inner mitochondrial membrane in response to high levels of Ca

Indexed as

alpha-SynucleinAmyloid beta-PeptidesAnimalsCalciumHumansMitochondriaMitochondrial MembranesMitochondrial Permeability Transition PoreMitochondrial Proton-Translocating ATPasesProtein Conformation, alpha-HelicalReactive Oxygen Speciesalpha-SynucleinAmyloid beta-PeptidesCalciummitochondrial ATPase subunit cMitochondrial Permeability Transition PoreMitochondrial Proton-Translocating ATPasesReactive Oxygen SpeciesSNCA protein, humanAmyloidogenic peptidesCalciumIon channelsMisfolded proteinsMitochondriaPermeability tradition pore

Identifiers

PMID33309700
PMCPMC12145140
OpenAlexW3110673544

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.