Evidence map›Paper›PMID 33309324›Full record

ReviewTrends in biochemical sciences2021

A Tour of TOR Complex Signaling in Plants.

Graham M Burkart, Federica Brandizzi

Abstract readReview
In one paragraph

Review in Trends in biochemical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Graham M BurkartMSU-DOE Plant Research Laboratory, Michigan State University, East Lansing, MI 48824, USA.
Federica BrandizziMSU-DOE Plant Research Laboratory, Michigan State University, East Lansing, MI 48824, USA; Department of Plant Biology, Michigan State University, East Lansing, MI 48824, USA; Great Lakes Bioenergy Research Center, Michigan State University, East Lansing, MI 48824, USA. Electronic address: fb@msu.edu.

Funding

Unfolded protein response in the model species Arabidopsis thalianaR35GM136637 · NIGMS · MICHIGAN STATE UNIVERSITY · PI Federica Brandizzi · 2020 to 2026
$2.6M
Unfolded protein response in the model species Arabidopsis thalianaR01GM101038 · NIGMS · MICHIGAN STATE UNIVERSITY · PI BRANDIZZI, FEDERICA · 2012 to 2019
$2.5M
NIGMS NIH HHS R01 GM101038NIGMS NIH HHS R35 GM136637
6 · The paper itself

Abstract

To identify the appropriate times for growth and development, organisms must sense and process information about the availability of nutrients, energy status, and environmental cues. For sessile eukaryotes such as plants, integrating such information can be critical in life or death decisions. For nearly 30 years, the conserved phosphatidylinositol 3-kinase-related protein kinases (PIKKs) target of rapamycin (TOR) has been established as a central hub for integrating external and internal metabolic cues. Despite the functional conservation across eukaryotes, the TOR complex has evolved specific functional and mechanistic features in plants. Here, we present recent findings on the plant TOR complex that highlight the conserved and unique nature of this critical growth regulator and its role in multiple aspects of plant life.

Indexed as

SirolimusTOR Serine-Threonine KinasesPlantsSignal TransductionSirolimusTOR Serine-Threonine Kinasesautophagycellular nutrition and homeostasiscircadian cycleenergy sensingphotosynthesisphytohormonessymbiotic relationships

Identifiers

PMID33309324
PMCPMC8052268

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.