Evidence map›Paper›PMID 33308661›Full record

ReviewThe Indian journal of tuberculosis2020

Hydroxychloroquine and COVID-19 - A narrative review.

Jyoti Bajpai, Akshyaya Pradhan, Abhishek Singh, Surya Kant

Abstract readReview
In one paragraph

Review in The Indian journal of tuberculosis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. The ecological impact of liquid chromatographic methods reported for bioanalysis of COVID-19 drug, hydroxychloroquine: Insights on greenness assessment.Microchemical journal : devoted to the application of microtechniques in all branches of science · 2023
    Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jyoti BajpaiDepartment of Respiratory Medicine, King George's Medical University, Lucknow, 226003, India.
Akshyaya PradhanDepartment of Cardiology, King George's Medical University, Lucknow, 226003, India.
Abhishek SinghDepartment of Medicine, King George's Medical University, Lucknow, 226003, India.
Surya KantDepartment of Respiratory Medicine, King George's Medical University, Lucknow, 226003, India. Electronic address: skantpulmed@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID 19 infection is unarguably the worst pandemic of this century. Till date there is no promising drug and vaccine available to treat this deadly viral infection. In the early phase chloroquine phosphate and hydroxychloroquine sulphate have been used to fight this illness on the basis of handful observational and small randomized and small-randomized studies. The paucity of clinical evidences of an unequivocal beneficial effect of chloroquine and hydroxychloroquine on COVID-19 has resulted in the passionate use of the drug for moderate to severe cases only and stimulated the need for large clinical trials for this and other molecules. In this review, we describe in brief the mechanism of action, the clinical studies, factors for cardiac toxicity, guidelines and future directions for hydroxychloroquine use in management of COVID-19 infection.

Indexed as

COVID-19 Drug TreatmentSARS-CoV-2Enzyme InhibitorsHumansHydroxychloroquineEnzyme InhibitorsHydroxychloroquineCOVID-19HydroxychloroquineImmunomodulatorPandemicQT prolongation

Identifiers

PMID33308661
PMCPMC7836863

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.