Evidence map›Paper›PMID 33308501›Full record

ReviewAdvances in chronic kidney disease2020

Pathophysiology and Pathology of Acute Kidney Injury in Patients With COVID-19.

Jia H Ng, Vanesa Bijol, Matthew A Sparks, Meghan E Sise, Hassane Izzedine, Kenar D Jhaveri

Abstract readReview
In one paragraph

Review in Advances in chronic kidney disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Positive fluid balance is associated with earlier acute kidney injury in COVID-19 patients.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2026
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14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jia H NgDivision of Kidney Diseases and Hypertension, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Great Neck, NY. Electronic address: Jng10@northwell.edu.
Vanesa BijolDepartment of Pathology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Great Neck, NY.
Matthew A SparksDivision of Nephrology, Department of Medicine, Duke University School of Medicine, Durham, NC; Renal Section, Durham Veterans Affairs Health Care System, Durham, NC.
Meghan E SiseDivision of Nephrology, Department of Medicine, Massachusetts General Hospital, Boston, MA.
Hassane IzzedineDepartment of Nephrology, Peupliers Private Hospital, Ramsay Générale de Santé, Paris, France.
Kenar D JhaveriDivision of Kidney Diseases and Hypertension, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Great Neck, NY.

Funding

Effect of Hepatitis C Virus Eradication on Chronic Kidney Disease ProgressionK23DK117014 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI SISE, MEGHAN E. · 2018 to 2022
$865k
NIDDK NIH HHS K23 DK117014
6 · The paper itself

Abstract

Acute kidney injury (AKI) is common among hospitalized patients with Coronavirus Infectious Disease 2019 (COVID-19), with the occurrence of AKI ranging from 0.5% to 80%. The variability in the occurrence of AKI has been attributed to the difference in geographic locations, race/ethnicity, and severity of illness. AKI among hospitalized patients is associated with increased length of stay and in-hospital deaths. Even patients with AKI who survive to hospital discharge are at risk of developing chronic kidney disease or end-stage kidney disease. An improved knowledge of the pathophysiology of AKI in COVID-19 is crucial to mitigate and manage AKI and to improve the survival of patients who developed AKI during COVID-19. The goal of this article is to provide our current understanding of the etiology and the pathophysiology of AKI in the setting of COVID-19.

Indexed as

Acute Kidney InjuryAnti-Bacterial AgentsAntiviral AgentsApolipoprotein L1Ascorbic AcidAzotemiaCOVID-19COVID-19 Drug TreatmentCytokinesDisease ProgressionGlomerulonephritisGlomerulonephritis, MembranousHospital MortalityHumansKidney Tubules, ProximalLength of StayAnti-Bacterial AgentsAntiviral AgentsApolipoprotein L1Ascorbic AcidCytokinesMyoglobinVitaminsAKICollapsing GNCOVID-19Kidney failurePathology

Identifiers

PMID33308501
PMCPMC7574722

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.