Evidence map›Paper›PMID 33308364›Full record

ReviewJournal of developmental origins of health and disease2021

The application of

Stephanie A Giza, Simran Sethi, Lauren M Smith, Mary-Ellen E T Empey, Lindsay E Morris, Charles A McKenzie

Abstract readReview
In one paragraph

Review in Journal of developmental origins of health and disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Magnetic resonance imaging of the monkey fetal brain in utero.Investigative magnetic resonance imaging · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Stephanie A GizaUniversity of Western Ontario, Schulich School of Medicine and Dentistry, Department of Medical Biophysics, 70384London, ON, Canada.
Simran SethiUniversity of Western Ontario, Schulich School of Medicine and Dentistry, Department of Medical Biophysics, 70384London, ON, Canada.
Lauren M SmithUniversity of Western Ontario, Schulich School of Medicine and Dentistry, Department of Medical Biophysics, 70384London, ON, Canada.
Mary-Ellen E T EmpeyUniversity of Western Ontario, Schulich School of Medicine and Dentistry, Department of Medical Biophysics, 70384London, ON, Canada.
Lindsay E MorrisUniversity of Western Ontario, Schulich School of Medicine and Dentistry, Department of Medical Biophysics, 70384London, ON, Canada.
Charles A McKenzieUniversity of Western Ontario, Schulich School of Medicine and Dentistry, Department of Medical Biophysics, 70384London, ON, Canada.ORCID 0000-0002-9614-1582

Funding

Hyperpolarized 13C MRI of Placental Metabolic Abnormalities Resulting from the Western DietU01HD087181 · NICHD · UNIVERSITY OF WESTERN ONTARIO · PI MCKENZIE, CHARLES A, REGNAULT, TIMOTHY RH · 2015 to 2015
$2.8M
CIHR 162308NICHD NIH HHS U01 HD087181
6 · The paper itself

Abstract

Observing fetal development in utero is vital to further the understanding of later-life diseases. Magnetic resonance imaging (MRI) offers a tool for obtaining a wealth of information about fetal growth, development, and programming not previously available using other methods. This review provides an overview of MRI techniques used to investigate the metabolic and cardiovascular consequences of the developmental origins of health and disease (DOHaD) hypothesis. These methods add to the understanding of the developing fetus by examining fetal growth and organ development, adipose tissue and body composition, fetal oximetry, placental microstructure, diffusion, perfusion, flow, and metabolism. MRI assessment of fetal growth, organ development, metabolism, and the amount of fetal adipose tissue could give early indicators of abnormal fetal development. Noninvasive fetal oximetry can accurately measure placental and fetal oxygenation, which improves current knowledge on placental function. Additionally, measuring deficiencies in the placenta's transport of nutrients and oxygen is critical for optimizing treatment. Overall, the detailed structural and functional information provided by MRI is valuable in guiding future investigations of DOHaD.

Indexed as

Fetal DevelopmentCardiovascular SystemFemaleFetal Growth RetardationFetusHumansMagnetic Resonance ImagingPlacentaPlacenta DiseasesPlacental CirculationPregnancyDevelopmental origins of health and diseasefetal developmentfetal growth restrictionMagnetic Resonance Imagingpregnancy

Identifiers

PMID33308364
PMCPMC8162788

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.