Evidence map›Paper›PMID 33308287›Full record

ArticleCardio-oncology (London, England)2020

A case report: rapid progression of coronary atherosclerosis in a patient taking Targretin (Bexarotene).

Sean DeAngelo, Kailyn I Mann, Muhammad Abdulbasit, Amy Ahnert, Deborah W Sundlöf

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardio-oncology (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Sean DeAngeloUniversity of South Florida/Lehigh Valley Hospital, 1200 South Cedar Crest Blvd, Allentown, PA, 18103, USA. seandea@pcom.edu.ORCID http://orcid.org/0000-0002-4576-945X
Kailyn I MannLehigh Valley Health Network, Heart Institute, Allentown, PA, USA.
Muhammad AbdulbasitLehigh Valley Health Network - Muhlenberg Department of Cardiology, Bethlehem, PA, USA.
Amy AhnertLehigh Valley Health Network, Heart Institute, Allentown, PA, USA.
Deborah W SundlöfPhiladelphia College of Osteopathic Medicine, Philadelphia, PA, USA.
Lehigh Valley Hospital-Pocono · USLehigh Valley Hospital · USLehigh Valley Hospital Muhlenberg · USPhiladelphia College of Osteopathic Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-neoplastic drugs have made major advancements in oncology, however they are not without cardiovascular consequences. We present a patient with cutaneous T-cell lymphoma receiving Targretin therapy who presented with accelerated atherosclerosis. His triglyceride level (TG) was greater than 1000 mg/dL, which rapidly improved with discontinuation of Targretin.

Indexed as

AtherosclerosisAtypical anginaCutaneous T-cell lymphomaPrimary hypertriglyceridemiaTargretin (Bexarotene)

Identifiers

PMID33308287
PMCPMC7734706
OpenAlexW3110725930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.