Evidence map›Paper›PMID 33308259›Full record

Trial reportJournal of the International Society of Sports Nutrition2020

Time-restricted eating effects on performance, immune function, and body composition in elite cyclists: a randomized controlled trial.

Tatiana Moro, Grant Tinsley, Giovanni Longo, Davide Grigoletto, Antonino Bianco, Cinzia Ferraris, Monica Guglielmetti, Alessandro Veneto, Anna Tagliabue, Giuseppe Marcolin and 1 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of the International Society of Sports Nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04320784 (Effects of 4 Weeks of Time Restricted Eating Protocol on Performance, Metabolism and Blood Outcomes in Elite Cyclists), which is not on this map. Cited by 80 papers, 19 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 19 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04320784 nacompletednot on this map

Effects of 4 Weeks of Time Restricted Eating Protocol on Performance, Metabolism and Blood Outcomes in Elite Cyclists

TypeinterventionalSponsorUniversity of PadovaRan2018 to 2018Enrolled16ConditionsFasting and PerformanceArmsTime restricted eating, Control
3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 19 syntheses or guidelines pooled it, 138 citations in OpenAlex.

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20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Tatiana MoroDepartment of Biomedical Science, University of Padova, Nutrition and Exercise Physiology Lab - Via Marzolo, 3, 35131, Padova, Italy.ORCID http://orcid.org/0000-0002-1404-1511
Grant TinsleyDepartment of Kinesiology & Sport Management, Texas Tech University, Lubbock, TX, USA.
Giovanni LongoDepartment of Biomedical Science, University of Padova, Nutrition and Exercise Physiology Lab - Via Marzolo, 3, 35131, Padova, Italy.
Davide GrigolettoDepartment of Biomedical Science, University of Padova, Nutrition and Exercise Physiology Lab - Via Marzolo, 3, 35131, Padova, Italy.
Antonino BiancoSport and Exercise Sciences Research Unit, University of Palermo, Palermo, Italy.
Cinzia FerrarisHuman Nutrition and Eating Disorder Research Center, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.
Monica GuglielmettiHuman Nutrition and Eating Disorder Research Center, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.
Alessandro VenetoHuman Nutrition and Eating Disorder Research Center, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.
Anna TagliabueHuman Nutrition and Eating Disorder Research Center, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.
Giuseppe MarcolinDepartment of Biomedical Science, University of Padova, Nutrition and Exercise Physiology Lab - Via Marzolo, 3, 35131, Padova, Italy.
Antonio PaoliDepartment of Biomedical Science, University of Padova, Nutrition and Exercise Physiology Lab - Via Marzolo, 3, 35131, Padova, Italy. antonio.paoli@unipd.it.
University of Padua · ITUniversity of Pavia · ITTexas Tech University · USUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough there is substantial interest in intermittent fasting as a dietary approach in active individuals, information regarding its effects in elite endurance athletes is currently unavailable. The present parallel randomized trial investigated the effects of a particular intermittent fasting approach, called time-restricted eating (TRE), during 4 weeks of high-level endurance training.

methodsSixteen elite under-23 cyclists were randomly assigned either to a TRE group or a control group (ND). The TRE group consumed 100% of its estimated daily energy needs in an 8-h time window (from 10:00 a.m. to 6:00 p.m.) whilst energy intake in the ND group was distributed in 3 meals consumed between 7:00 a.m. and 9:00 p.m. Fat and fat-free mass were estimated by bioelectrical impedance analysis and VO

resultsTRE reduced body weight (- 2%; p = 0.04) and fat mass percentage (- 1.1%; p = 0.01) with no change in fat-free mass. Performance tests showed no significant differences between groups, however the peak power output/body weight ratio (PPO/BW) improved in TRE group due to weight loss (p = 0.02). Free testosterone and IGF-1 decreased significantly (p = 0.01 and p = 0.03 respectively) in TRE group. Leucocyte count decreased in ND group (p = 0.02) whilst the neutrophils-to-lymphocytes ratio (NLR) decreased significantly (p = 0.03) in TRE group.

conclusionsOur results suggest that a TRE program with an 8-h feeding window elicits weight loss, improves body composition and increases PPO/BW in elite cyclists. TRE could also be beneficial for reducing inflammation and may have a protective effect on some components of the immune system. Overall, TRE could be considered as a component of a periodized nutrition plan in endurance athletes.

trial registrationThis trial was retrospectively registered at clinicaltrials.gov as NCT04320784 on 25 March 2020.

Indexed as

AthletesAthletic PerformanceBasal MetabolismBicyclingBody CompositionCreatinineDietElectric ImpedanceEnergy IntakeFastingHumansImmune SystemInsulin-Like Growth Factor IInterleukin-6Leukocyte CountLymphocyte CountCreatinineInsulin-Like Growth Factor IInterleukin-6TestosteroneTransforming Growth Factor alphaElite cyclistsEnduranceImmune systemInflammationIntermittent fasting

Identifiers

PMID33308259
PMCPMC7733258
OpenAlexW3111436189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.