Evidence map›Paper›PMID 33307984›Full record

ArticleLupus2021

Low prevalence of bone mineral density testing in patients with systemic lupus erythematosus and glucocorticoid exposure.

J B Boone, Lee Wheless, Alex Camai, S Bobo Tanner, April Barnado

Open access · greenAbstract read
In one paragraph

Article in Lupus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Logistic Entropy of Trabecular Bone Score in SLE Patients and New Type Visualizations.Computational and mathematical methods in medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

J B BooneDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Lee WhelessDepartment of Dermatology, Data Science Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Alex CamaiDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
S Bobo TannerDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
April BarnadoDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID https://orcid.org/0000-0002-9573-4335
Vanderbilt University Medical Center · US

Funding

VANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Using the electronic health record to risk-stratify patients with systemic lupus erythematosusK08AR072757 · NIAMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BARNADO, APRIL LYNN · 2018 to 2022
$817k
NCATS NIH HHS UL1 TR000445NCRR NIH HHS UL1 RR024975NIAMS NIH HHS K08 AR072757
6 · The paper itself

Abstract

SummaryPatients with systemic lupus erythematosus (SLE) have an increased risk of developing osteoporosis and fractures due to systemic inflammation and glucocorticoids (GCs). Professional organizations recommend bone mineral density (BMD) testing in SLE patients on GCs, especially within 6 months of initiation. Using a validated algorithm, we identified SLE patients in an electronic health record cohort with long-term GC exposure (≥90 days). Our primary outcome was ever BMD testing. We assessed the impact of patient and provider factors on testing. We identified 693 SLE cases with long-term GC exposure, 41% of whom had BMD testing performed. Only 18% of patients had BMD testing within 6 months of GC initiation. In a logistic regression model for BMD testing, male sex (OR = 0.49, 95% CI 0.27 - 0.87, p = 0.01) was associated with being less likely to have BMD testing after adjusting for race and ethnicity. In contrast, older age (OR = 1.04, p < 0.001) and nephritis (OR = 1.83, p = 0.003) were associated with being more likely to have BMD testing after adjusting for race and ethnicity. Bone health in SLE patients remains an area in need of improvement with attention to patients who are younger and male.

Indexed as

Bone DensityAbsorptiometry, PhotonAdultAgedDatabases, FactualFemaleGlucocorticoidsHumansLupus Erythematosus, SystemicMaleMiddle AgedOsteoporosisRetrospective StudiesRheumatologyGlucocorticoidsbone mineral densityelectronic health recordsSystemic lupus erythematosus

Identifiers

PMID33307984
PMCPMC7933066
OpenAlexW3112259624

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.