Evidence map›Paper›PMID 33307864›Full record

SynthesisIntegrative cancer therapies

Acupuncture for Radiation-Induced Xerostomia in Cancer Patients: A Systematic Review and Meta-Analysis.

Xixiu Ni, Tian Tian, Dan Chen, Lu Liu, Xiao Li, Fengmei Li, Fanrong Liang, Ling Zhao

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Integrative cancer therapies. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06465628 (Effect of Self-administered Acupressure for Improving Xerostomia in Head and Neck Cancer Patients), which is not on this map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06465628 narecruitingnot on this map

Effect of Self-administered Acupressure for Improving Xerostomia in Head and Neck Cancer Patients: a Randomized Controlled Trial

TypeinterventionalSponsorThe University of Hong KongRan2024 to 2027Enrolled126ConditionsHead and Neck Cancer, XerostomiaArmsSelf-administered acupressure, Oral health education
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. A systematic review of salivary gland hypofunction and/or xerostomia induced by non-surgical cancer therapies: prevention strategies.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Review
  6. Acupuncture in cancer care: a narrative review.Revista da Associacao Medica Brasileira (1992) · 2024
    Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Observational
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xixiu NiChengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.ORCID 0000-0001-7359-6173
Tian TianChengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Dan Chen
Lu LiuChengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Xiao LiChengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Fengmei LiChengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Fanrong LiangChengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Ling ZhaoChengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Chengdu University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRadiation-induced xerostomia is one of the most common symptoms experienced by cancer patients. The aim of our study is to evaluate the preventive and therapeutic effect of acupuncture for radiation-induced xerostomia in cancer patients.

methodsEight databases were searched for all published randomized clinical trials (RCTs) on acupuncture for radiation-induced xerostomia in cancer patients up to December 31, 2019. Manual searching included other conference abstracts and reference lists. Meta-analysis was conducted using Revman V.5.3, and risks of bias for included studies was assessed following the Cochrane Handbook.

resultsEight clinical trials (725 participants) were analyzed, and 3 were included in a meta-analysis. All included trials had a high risk of bias, such as selection, performance, and detection bias. Analysis indicated favorable effects of acupuncture regarding the improvement of xerostomia symptoms (MD -3.05,

conclusionThe present meta-analysis and systematic review suggests that acupuncture is effective at improving xerostomia symptoms in cancer patients but not at objective salivary flow measurements. The evidence is still limited due to the low quality of the published studies.

Indexed as

Acupuncture TherapyNeoplasmsXerostomiaHumansacupuncturecancersystematic reviewsxerostomia

Identifiers

PMID33307864
PMCPMC7739209
OpenAlexW3111008664

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.