ReviewOsteoarthritis and cartilage2021
Blood in the joint: effects of hemarthrosis on meniscus health and repair techniques.
Review in Osteoarthritis and cartilage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
20 citing papers in PubMed, 26 citations in OpenAlex.
- Article
- Musculoskeletal ultrasound in traumatic emergencies: what radiologists need to know.La Radiologia medica · 2026Review
- [Advances in immunomodulatory strategies for meniscal regeneration].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026Review
- Platelet-rich plasma facilitates earlier functional recovery and return to sport in traumatic meniscal repair: a retrospective cohort study.Journal of orthopaedic surgery and research · 2026Article
- Synovial Fluid Characteristics and Pain Recovery Trajectory Following Rehabilitation in Patients with Meniscal Tears: A Retrospective Cohort Study.Healthcare (Basel, Switzerland) · 2026Article
- Long-term impact of acute knee injury with hemarthrosis: Osteoarthritis incidence and patient-reported outcomes in a large consecutive cohort over 12 years.Osteoarthritis and cartilage open · 2025Article
- Dihydroartemisinin ameliorates hemarthrosis-induced cartilage degeneration by suppressing chondrocyte senescence via activation of Keap1-Nrf2 signaling pathway.Journal of orthopaedic translation · 2025Article
- Increasing the concentration of plasma molecules improves the biological activity of platelet-rich plasma for tissue regeneration.Scientific reports · 2025Article
- Proteomic exploration of potential blood biomarkers in haemophilic arthropathy.Health science reports · 2024Article
- Shedding light on the effects of blood on meniscus tissue: the role of mononuclear leukocytes in mediating meniscus catabolism.Osteoarthritis and cartilage · 2024Article
- Effect of Blood on Synovial Joint Tissues: Potential Role of Ferroptosis.Applied sciences (Basel, Switzerland) · 2024Article
- Outcome of meniscal repairs in paediatric population: A tertiary centre experience.World journal of orthopedics · 2024Article
- Outcome measures analysis following total knee arthroplasty in patients with severe haemophilic arthropathy of the knee.Biomedical reports · 2024Article
- A pathological joint-liver axis mediated by matrikine-activated CD4Signal transduction and targeted therapy · 2024Article
- Current Challenges in the Development of Platelet-Rich Plasma-Based Therapies.BioMed research international · 2024Review
- Terminal complement complex deposition on chondrocytes promotes premature senescence in age- and trauma-related osteoarthritis.Frontiers in immunology · 2024Article
- Red blood cell exposure increases chondrocyte susceptibility to oxidative stress following hemarthrosis.Osteoarthritis and cartilage · 2023Article
- Erythrocyte removal from bone marrow aspirate concentrate improves efficacy as intra-articular cellular therapy in a rodent osteoarthritis model.Annals of translational medicine · 2023Article
- Articular fragment restoration is critical to mitigate post-traumatic osteoarthritis in a porcine pilon fracture model.Osteoarthritis and cartilage open · 2022Article
- Predictive Variables for Interventional Angiography among Patients with Knee Hemarthrosis.Diagnostics (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Injury to the meniscus is common and frequently leads to the development of post-traumatic osteoarthritis (PTOA). Many times meniscus injuries occur coincident with anterior cruciate ligament (ACL) injuries and lead to a bloody joint effusion. Hemarthrosis, or bleeding into the joint, has been implicated in degeneration of joint tissues. The goal of this review paper is to understand the pathophysiology of blood-induced joint damage, the possible effects of blood on meniscus tissue, and the implications for current meniscus repair techniques that involve the introduction of blood-derived products into the joint. In this review, we illustrate the similarities in the pathophysiology of joint damage due to hemophilic arthropathy (HA) and osteoarthritis (OA). Although numerous studies have revealed the harmful effects of blood on cartilage and synovium, there is currently a gap in knowledge regarding the effects of hemarthrosis on meniscus tissue homeostasis, healing, and the development of PTOA following meniscus injury. Given that many meniscus repair techniques utilize blood-derived and marrow-derived products, it is essential to understand the effects of these factors on meniscus tissue and the whole joint organ to develop improved strategies to promote meniscus tissue repair and prevent PTOA development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.