Evidence map›Paper›PMID 33306713›Full record

ArticlePloS one2020

Health, educational and employment outcomes among children treated for a skin disorder: Scotland-wide retrospective record linkage cohort study of 766,244 children.

Michael Fleming, James S McLay, David Clark, Albert King, Daniel F Mackay, Jill P Pell

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Michael FlemingInstitute of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom.ORCID 0000-0002-2185-4502
James S McLayDepartment of Child Health, University of Aberdeen, Aberdeen, United Kingdom.
David ClarkPublic Health Scotland, Edinburgh, United Kingdom.
Albert KingScotXed, Scottish Government, Edinburgh, United Kingdom.
Daniel F MackayInstitute of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom.
Jill P PellInstitute of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom.
University of Glasgow · GBPublic Health Scotland · GBScottish Government · GBUniversity of Aberdeen · GB

Funding

British Heart FoundationChief Scientist OfficeDepartment of HealthMedical Research Council MR/S003800/1Wellcome Trust
6 · The paper itself

Abstract

backgroundTo compare health, educational and employment outcomes of schoolchildren receiving medication for a skin disorder with peers.

methodsThis retrospective population cohort study linked eight Scotland-wide databases, covering dispensed prescriptions, hospital admissions, maternity records, death certificates, annual pupil census, school examinations, school absences/exclusions and unemployment to investigate educational (absence, exclusion, special educational need, academic attainment), employment, and health (admissions and mortality) outcomes of 766,244 children attending local authority run primary, secondary and special schools in Scotland between 2009 and 2013.

resultsAfter adjusting for sociodemographic and maternity confounders the 130,087 (17.0%) children treated for a skin disorder had increased hospitalisation, particularly within one year of commencing treatment (IRR 1.38, 95% CI 1.35-1.41, p<0.001) and mortality (HR 1.50, 95% CI 1.18-1.90, p<0.001). They had greater special educational need (OR 1.19, 95% CI 1.17-1.21, p<0.001) and more frequent absences from school (IRR 1.07, 95% CI 1.06-1.08, p<0.001) but did not exhibit poorer exam attainment or increased post-school unemployment. The associations remained after further adjustment for comorbid chronic conditions.

conclusionsDespite increased hospitalisation, school absenteeism, and special educational need, children treated for a skin disorder did not have poorer exam attainment or employment outcomes. Whilst findings relating to educational and employment outcomes are reassuring, the association with increased risk of mortality is alarming and merits further investigation.

Indexed as

MortalityAbsenteeismAdolescentAdultAsthmaAttention Deficit Disorder with HyperactivityChildChild, PreschoolDatabases, FactualDepressionEczemaEducational StatusEducation, SpecialFemaleHospitalizationHumans

Identifiers

PMID33306713
PMCPMC7732076
OpenAlexW3111881738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.