Evidence map›Paper›PMID 33306316›Full record

ArticleBrazilian journal of cardiovascular surgery2020

Cardiac Output Values and Correlation of Renal Injury with Neutrophil Gelatinase-Associated Lipocalin Levels in Off-Pump Coronary Artery Bypass Patients.

Şahin Şahinalp, Zeki Temiztürk, Kadir Çeviker, Kanat Özışık, Uğursay Kızıltepe

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Article in Brazilian journal of cardiovascular surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Observational
4 · The record

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5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Şahin ŞahinalpDepartment of Cardiovascular Surgery, Faculty of Medicine, Van Yuzuncu Yil University, Van, Turkey.
Zeki TemiztürkDepartment of Cardiovascular Surgery, Elazig Education and Research Hospital, University of Health Sciences, Elazig, Turkey.
Kadir ÇevikerDepartment of Cardiovascular Surgery, Western Anatolia Central Hospital, Izmir, Turkey.
Kanat ÖzışıkDepartment of Cardiovascular Surgery, Ankara City Hospital, Ankara, Turkey.
Uğursay KızıltepeDepartment of Cardiovascular Surgery, Diskapi Yildirim Beyazit Education and Research Hospital, University of Health Sciences, Ankara, Turkey.
Memorial Ankara Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the correlation between cardiac output values and renal neutrophil gelatinase-associated lipocalin (NGAL) levels as a biomarker of renal ischemia.

methodsForty patients, who underwent off-pump coronary artery bypass (OPCAB) surgery and in whom the positioning of the heart was fixed with simple suspension sutures without a mechanical stabilizer, were included in the study. Continuous cardiac output (CO) measurements were recorded using the arterial pressure waveform analysis method (FloTrac sensor system) in the perioperative period. CO was recorded every minute during non-anatomical cardiac positioning for left anterior descending artery (LAD), diagonal artery (D), circumflex artery (Cx), and right coronary artery (RCA) bypasses. Serum NGAL samples were analyzed in the preoperative, perioperative, and postoperative periods.

resultsThe CO values measured at various non-anatomical cardiac positions during distal anastomosis for LAD, D, Cx, and RCA were significantly lower than pre- and postoperative values measured with the heart in normal anatomical position (3.45±0.78, 2.9±0.71, 3.11±0.56, 3.19±0.81, 5.03±1.4, and 4.85±0.78, respectively, P=0.008). There was no significant difference between CO values measured at various non-anatomical cardiac positions during distal anastomosis. Although there was no significant correlation between NGAL levels and age, duration of surgery, preoperative CO, D-CO, RCA-CO, and postoperative CO measurements, there was a significant correlation between NGAL levels and LAD-CO (P=0.044) and Cx-CO (P=0.018) at the postoperative 12th hour.

conclusionFull revascularization may be achieved by employing the OPCAB technique while using simple suspension sutures without a mechanical stabilizer and by providing safe CO levels and low risk of renal ischemia.

Indexed as

Coronary Artery Bypass, Off-PumpCardiac OutputCoronary VesselsHumansKidneyLipocalin-2MaleLipocalin-2Anastomosis, SurgicalArterial PressureBiomarkersCardiac OutputCoronary Artery Bypass, Off-PumpCoronary VesselsLipocalin-2Longitudinal Studies

Identifiers

PMID33306316
PMCPMC7731851
OpenAlexW3100977598

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.