Evidence map›Paper›PMID 33305571›Full record

ArticleJournal of the American Chemical Society2020

Selective Chemical Functionalization at N6-Methyladenosine Residues in DNA Enabled by Visible-Light-Mediated Photoredox Catalysis.

Manuel Nappi, Alexandre Hofer, Shankar Balasubramanian, Matthew J Gaunt

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Selective Functionalisation of 5-Methylcytosine by Organic Photoredox Catalysis.Angewandte Chemie (International ed. in English) · 2023
    Article
  4. Selective Functionalisation of 5-Methylcytosine by Organic Photoredox Catalysis.Angewandte Chemie (Weinheim an der Bergstrasse, Germany) · 2023
    Article
  5. Article
  6. Transcriptome-wide profiling ofChemical science · 2022
    Article
  7. Genome-wide mapping ofChemical science · 2022
    Article
  8. Article
  9. Article
  10. Review
  11. Minimization of Back-Electron Transfer Enables the Elusive spAngewandte Chemie (International ed. in English) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Manuel NappiDepartment of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom.ORCID 0000-0002-3023-0574
Alexandre HoferDepartment of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom.ORCID 0000-0001-6396-3689
Shankar BalasubramanianDepartment of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom.ORCID 0000-0002-0281-5815
Matthew J GauntDepartment of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom.ORCID 0000-0002-7214-608X
University of Cambridge · GB

Funding

Cancer Research UK 18618Cancer Research UK C14303/A17197Cancer Research UK C9681/A18618Wellcome TrustWellcome Trust 209441/Z/17/Z
6 · The paper itself

Abstract

Selective chemistry that modifies the structure of DNA and RNA is essential to understanding the role of epigenetic modifications. We report a visible-light-activated photocatalytic process that introduces a covalent modification at a C(sp

Indexed as

LightPhotochemical ProcessesAdenosineAminesCatalysisDNAHydrogenMethylationNitrogenOxidation-ReductionAdenosineAminesDNAHydrogenNitrogen

Identifiers

PMID33305571
PMCPMC7760100
OpenAlexW3112885987

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.