ArticleVirchows Archiv : an international journal of pathology2021
The histopathological diagnosis of atypical meningioma: glass slide versus whole slide imaging for grading assessment.
Article in Virchows Archiv : an international journal of pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Technical and Diagnostic Issues in Whole Slide Imaging Published Validation Studies.Frontiers in oncology · 2022Pooled it
- Molecular classification to refine surgical and radiotherapeutic decision-making in meningioma.Nature medicine · 2024Article
- Meningioma: International Consortium on Meningiomas consensus review on scientific advances and treatment paradigms for clinicians, researchers, and patients.Neuro-oncology · 2024Review
- Atypical Imaging Features of an Incidentally Discovered Intracranial Meningioma: A Case Report.Cureus · 2024Article
- Descriptive epidemiology of 30,223 histopathologically confirmed meningiomas in France: 2006-2015.Acta neurochirurgica · 2024Article
- Leveraging Attention-Based Convolutional Neural Networks for Meningioma Classification in Computational Histopathology.Cancers · 2023Article
- Virtual Versus Light Microscopy Usage among Students: A Systematic Review and Meta-Analytic Evidence in Medical Education.Diagnostics (Basel, Switzerland) · 2023Review
- Clinical Implications of the Mitotic Index as a Predictive Factor for Malignant Transformation of Atypical Meningiomas.Journal of Korean Neurosurgical Society · 2022Article
- Lost in digitization - A systematic review about the diagnostic test accuracy of digital pathology solutions.Journal of pathology informatics · 2022Review
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 3 countries.
Funding
Abstract
Limited studies on whole slide imaging (WSI) in surgical neuropathology reported a perceived limitation in the recognition of mitoses. This study analyzed and compared the inter- and intra-observer concordance for atypical meningioma, using glass slides and WSI. Two neuropathologists and two residents assessed the histopathological features of 35 meningiomas-originally diagnosed as atypical-in a representative glass slide and corresponding WSI. For each histological parameter and final diagnosis, we calculated the inter- and intra-observer concordance in the two viewing modes and the predictive accuracy on recurrence. The concordance rates for atypical meningioma on glass slides and on WSI were 54% and 60% among four observers and 63% and 74% between two neuropathologists. The inter-observer agreement was higher using WSI than with glass slides for all parameters, with the exception of high mitotic index. For all histological features, we found median intra-observer concordance of ≥ 79% and similar predictive accuracy for recurrence between the two viewing modes. The higher concordance for atypical meningioma using WSI than with glass slides and the similar predictive accuracy for recurrence in the two modalities suggest that atypical meningioma may be safely diagnosed using WSI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.