Evidence map›Paper›PMID 33305150›Full record

ArticleHepatology communications2020

Elevated Glycated Hemoglobin Is Associated With Liver Fibrosis, as Assessed by Elastography, in a Population-Based Study of Mexican Americans.

Gordon P Watt, Isela De La Cerda, Jen-Jung Pan, Michael B Fallon, Laura Beretta, Rohit Loomba, Miryoung Lee, Joseph B McCormick, Susan P Fisher-Hoch

Open access · goldAbstract read
In one paragraph

Article in Hepatology communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

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  12. Assessing Interactions betweenInternational journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Gordon P WattDepartment of Epidemiology and Biostatistics Memorial Sloan Kettering Cancer Center New York NY USA.
Isela De La CerdaDivision of Epidemiology Human Genetics and Environmental Health University of Texas Health Science Center at Houston School of Public Health. Brownsville campus Brownsville TX USA.ORCID https://orcid.org/0000-0003-3625-8954
Jen-Jung PanDivision of Gastroenterology and Hepatology Department of Medicine The University of Arizona College of Medicine-Phoenix Phoenix AZ USA.
Michael B FallonDepartment of Medicine The University of Arizona College of Medicine-Phoenix Phoenix AZ USA.
Laura BerettaDepartment of Molecular and Cellular Oncology The University of Texas MD Anderson Cancer Center Houston TX USA.ORCID https://orcid.org/0000-0002-2054-684X
Rohit LoombaNAFLD Research Center Division of Gastroenterology University of California San Diego School of Medicine La Jolla CA USA.ORCID https://orcid.org/0000-0002-4845-9991
Miryoung LeeDivision of Epidemiology Human Genetics and Environmental Health University of Texas Health Science Center at Houston School of Public Health. Brownsville campus Brownsville TX USA.
Joseph B McCormickDivision of Epidemiology Human Genetics and Environmental Health University of Texas Health Science Center at Houston School of Public Health. Brownsville campus Brownsville TX USA.
Susan P Fisher-HochDivision of Epidemiology Human Genetics and Environmental Health University of Texas Health Science Center at Houston School of Public Health. Brownsville campus Brownsville TX USA.
University of Arizona · USMemorial Sloan Kettering Cancer Center · USThe University of Texas MD Anderson Cancer Center · USUniversity of California San Diego · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Convalescent Plasma to Limit Coronavirus Associated ComplicationsUL1TR003167 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KARP, DANIEL D, MCPHERSON, DAVID D · 2019 to 2023
$45.3M
San Diego Digestive Diseases Research CenterP30DK120515 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LARS ECKMANN, Bernd G. Schnabl · 2019 to 2026
$10.8M
NCATS NIH HHS UL1 TR003167NCI NIH HHS P30 CA008748NIDDK NIH HHS P30 DK120515
6 · The paper itself

Abstract

Diabetes is associated with liver disease and risk of hepatocellular carcinoma. In this study, we evaluated the association between liver fibrosis measured by transient elastography and four glucose metabolism measures in the Cameron County Hispanic Cohort, a population-based, randomly selected cohort of Mexican American Hispanics with high rates of diabetes and liver cancer. We measured liver fibrosis (a risk factor for hepatocellular carcinoma) in 774 well-characterized cohort participants using transient elastography. We evaluated the association of liver fibrosis with glycated hemoglobin (HbA1c), fasting blood glucose, insulin, and insulin resistance using multivariable linear regression models. In multivariable models, log-transformed HbA1c had the strongest association with liver fibrosis (β = 0.37, 95% confidence interval [CI] 0.04-0.69,

Identifiers

PMID33305150
PMCPMC7706295
OpenAlexW3096013683

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.