Evidence map›Paper›PMID 33304739›Full record

ArticleChemistryOpen2020

Kinetic Target-Guided Synthesis of Small-Molecule G-Quadruplex Stabilizers.

Alice Pomeislová, Lukáš Vrzal, Jaroslav Kozák, Juraj Dobiaš, Martin Hubálek, Hana Dvořáková, Paul E Reyes-Gutiérrez, Filip Teplý, Václav Veverka

Open access · goldAbstract read
In one paragraph

Article in ChemistryOpen, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Alice PomeislováInstitute of Organic Chemistry and Biochemistry, The Czech Academy of Sciences Flemingovo nam. 2, Prague, Czech Republic.
Lukáš VrzalInstitute of Organic Chemistry and Biochemistry, The Czech Academy of Sciences Flemingovo nam. 2, Prague, Czech Republic.
Jaroslav KozákInstitute of Organic Chemistry and Biochemistry, The Czech Academy of Sciences Flemingovo nam. 2, Prague, Czech Republic.
Juraj DobiašInstitute of Organic Chemistry and Biochemistry, The Czech Academy of Sciences Flemingovo nam. 2, Prague, Czech Republic.
Martin HubálekInstitute of Organic Chemistry and Biochemistry, The Czech Academy of Sciences Flemingovo nam. 2, Prague, Czech Republic.
Hana DvořákováNMR laboratory, University of Chemistry and Technology, Prague, Czech Republic.
Paul E Reyes-GutiérrezInstitute of Organic Chemistry and Biochemistry, The Czech Academy of Sciences Flemingovo nam. 2, Prague, Czech Republic.
Filip TeplýInstitute of Organic Chemistry and Biochemistry, The Czech Academy of Sciences Flemingovo nam. 2, Prague, Czech Republic.
Václav VeverkaInstitute of Organic Chemistry and Biochemistry, The Czech Academy of Sciences Flemingovo nam. 2, Prague, Czech Republic.ORCID 0000-0003-3782-5279
Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry · CZCharles University · CZUniversity of Chemistry and Technology, Prague · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The formation of a G-quadruplex motif in the promoter region of the

Indexed as

Aniline CompoundsChemistry Techniques, SyntheticClick ChemistryGenes, mycG-QuadruplexesKineticsLigandsMolecular Dynamics SimulationanilineAniline CompoundsLigandsanticancer therapyclick chemistryG-quadruplexNMRsecondary structures

Identifiers

PMID33304739
PMCPMC7713561
OpenAlexW3109400547

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.