Evidence map›Paper›PMID 33304721›Full record

ArticleJournal of general and family medicine2020

A case of laryngopharyngeal reflux-associated chronic cough: Misinterpretation of treatment efficacy causes diagnostic delay.

Asuka Kikuchi, Ryuichi Kawamoto, Junki Mizumoto, Taichi Akase, Daisuke Ninomiya, Teru Kumagi

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of general and family medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Asuka KikuchiDepartment of Community Medicine Graduate School of Medicine Ehime University Ehime Japan.ORCID https://orcid.org/0000-0001-9329-9125
Ryuichi KawamotoDepartment of Community Medicine Graduate School of Medicine Ehime University Ehime Japan.
Junki MizumotoDepartment of Family Practice Ehime Seikyou Hospital Ehime Japan.ORCID https://orcid.org/0000-0002-0783-7351
Taichi AkaseDepartment of Community Medicine Graduate School of Medicine Ehime University Ehime Japan.
Daisuke NinomiyaDepartment of Community Medicine Graduate School of Medicine Ehime University Ehime Japan.
Teru KumagiDepartment of Community Medicine Graduate School of Medicine Ehime University Ehime Japan.
Ehime University · JPEhime Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 62-year-old woman presented with a dry cough lasting 18 months. She had previously been examined by multiple doctors, but no abnormalities were observed. Several medications such as rabeprazole and inhaled corticosteroids were administered as test treatments without any improvement. Therefore, the possibility of biological disease, including acid reflux, had been mistakenly ruled out. We examined the sputum gram stain. The result showed phagocyted normal bacterial flora, suggesting aspiration. Laryngoscopy revealed edema of the arytenoid cartilage. The patient was finally diagnosed with laryngopharyngeal reflux and silent aspiration. This case suggested that the ineffectiveness of proton-pump inhibitors cannot always exclude the presence of reflux disease and the usefulness of gram stain examination to detect silent aspiration.

Indexed as

chronic coughlaryngopharyngeal refluxmosaprideproton‐pump inhibitorsilent aspiration

Identifiers

PMID33304721
PMCPMC7689238
OpenAlexW3043810128

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.