ArticleJournal of general and family medicine2020
Restless legs syndrome induced by fexofenadine/pseudoephedrine.
Article in Journal of general and family medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- Supporting respiratory epithelia and lowering inflammation to effectively treat common cold symptoms: A randomized controlled trial.PloS one · 2024Trial
- Restless Legs Syndrome Associated With Fexofenadine Use: A Case Report.Clinical case reports · 2026Article
- Restless leg syndrome in spinal cord injury: case report.Spinal cord series and cases · 2023Article
- Restless legs syndrome induced by fexofenadine/pseudoephedrine.Journal of general and family medicine · 2020Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antihistamines are known risk factors for restless legs syndrome (RLS). However, reports on RLS associated with fexofenadine or its combinations are rare. Here, we report a 30-year-old woman with RLS that was induced by fexofenadine/pseudoephedrine. She had been taking fexofenadine/pseudoephedrine for three months and felt a strong urge to move her legs at night, which was relieved by movement. Her condition improved by taking pramipexole, which she discontinued subsequently because of dizziness. One month later, she quitted taking fexofenadine/pseudoephedrine, after which her symptoms disappeared a week later. This case study demonstrates that RLS can be induced by fexofenadine/pseudoephedrine and we should always consider the possibility of drug-induced RLS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.