Evidence map›Paper›PMID 33303963›Full record

ArticleCommunications biology2020

Somatostatin expressing GABAergic interneurons in the medial entorhinal cortex preferentially inhibit layer

Miklós Kecskés, Nóra Henn-Mike, Ágnes Agócs-Laboda, Szilárd Szőcs, Zoltán Petykó, Csaba Varga

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Involvement of GABAergic Interneuron Subtypes in 4-Aminopyridine-Induced Seizure-Like Events in Mouse Entorhinal CortexThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  8. Review
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Miklós KecskésSzentágothai Research Center, Department of Physiology, Medical School, University of Pécs, Pécs, 7624, Hungary.ORCID 0000-0002-0240-0476
Nóra Henn-MikeSzentágothai Research Center, Department of Physiology, Medical School, University of Pécs, Pécs, 7624, Hungary.ORCID 0000-0003-0786-3899
Ágnes Agócs-LabodaSzentágothai Research Center, Department of Physiology, Medical School, University of Pécs, Pécs, 7624, Hungary.ORCID 0000-0002-0591-8457
Szilárd SzőcsSzentágothai Research Center, Department of Physiology, Medical School, University of Pécs, Pécs, 7624, Hungary.ORCID 0000-0001-7185-1871
Zoltán PetykóSzentágothai Research Center, Department of Physiology, Medical School, University of Pécs, Pécs, 7624, Hungary.
Csaba VargaSzentágothai Research Center, Department of Physiology, Medical School, University of Pécs, Pécs, 7624, Hungary. csaba.varga@aok.pte.hu.ORCID 0000-0002-9188-1282
University of Pecs · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GABA released from heterogeneous types of interneurons acts in a complex spatio-temporal manner on postsynaptic targets in the networks. In addition to GABA, a large fraction of GABAergic cells also express neuromodulator peptides. Somatostatin (SOM) containing interneurons, in particular, have been recognized as key players in several brain circuits, however, the action of SOM and its downstream network effects remain largely unknown. Here, we used optogenetics, electrophysiologic, anatomical and behavioral experiments to reveal that the dendrite-targeting, SOM

Indexed as

Gene ExpressionAnimalsBiomarkersCell CommunicationElectrophysiological PhenomenaEntorhinal CortexFemaleGABAergic NeuronsInterneuronsMaleMemory, Short-TermMiceMice, KnockoutNeural PathwaysNeurotransmitter AgentsPeptidesBiomarkersNeurotransmitter AgentsPeptidesSomatostatin

Identifiers

PMID33303963
PMCPMC7728756
OpenAlexW3112127784

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.